Varicella Zoster

Question: How does the Varicella-zoster virus interact with the body to cause the symptoms of chickenpox?

Answer: What you're asking is what is the pathophysiology of the disease, right? The virus enters the respiratory tract and quickly replicates. VZV is an enveloped, double-stranded DNA virus. It attaches to the wall of the cell it invades and then enters the cell. The virus uncoats and is transported to the nucleus where the viral DNA replicates creating new virions that are eventually released from the cell to infect other cells. Since there's gas exchange in the respiratory tract, the virus is certainly small enough to enter the blood and then is carried through the bloodstream to the skin where it causes a rash. While the virus is in the bloodstream (before the rash begins) it causes typical viral symptoms like fever, fatigue, joint pains, headache, and swollen glands. These are immune responses. Kinda fundamental. Are you asking this because you have homework to finish?

Question: What kingdom does the virus Varicella-Zoster Virus(VZV) belong to? alsooo i need what phylum it is in too.

Answer: Virus do not belong to the 5 kingdom of life classification. Viruses are not defined as a living organism therefore they do not belong to a kingdom or phylum.

Question: Does the pathogen Varicella Zoster Virus affect other animals other than humans?

Answer: Yes. VZV can infect all members of the Homininae subfamily of primates: humans, chimpanzees and gorillas, but it doesn't appear to affect other animals including the other great apes (the orang utans) or carnivores such as cats and dogs. http://www.ncbi.nlm.nih.gov/pubmed/2826674?dopt=Abstract

Question: how does varicella zoster virus cause the disruption of human health?

Answer: Interested in the answers. I would guess a virus in the body would cause various disruptions. Might mask other health problems. Compromise your immune system. False readings of white blood cells. Tagger

Question: PLEASE HELP ME!!!! does the varicella zoster virus (chicken pox and shingles) have DNA or RNA? I NEED TO KNOW BY TOMORO!!! does the varicella zoster virus have DNA or RNA??? i need to know. so if u could please find out and tell me or if u already know please answer. thank youu!!!

Answer: It is a DNA virus. The only RNA virus that i know of is Hepatitis A. as compare to other heps that all are DNA.

Question: Shingles,chickenpox and varicella-zoster-herpes? Shingles and chickenpox are diseases caused by the varicella-zoster-herpes virus. Shingles usually occur after a person has had chickenpox. Based on this info, what kind of infection cycle do you think the varicella-zoster-herpes virus has? Link the infection cycle to the appearance to shingles years after the initial infection with the virus.

Answer: When you are infected with the virus the first time, you get chicken pox. When the chicken pox goes away, the virus stays in your body, but it lies dormant in nerve cells. Then in some people it is reactivated many years later (no-one is totally sure why - maybe stress etc) and the virus multiplies and travels back up the nerve to the skin, where it causes shingles. This is why shingles is so painful - it is basically a nerve infection. The same kind of thing happens with cold sores - it's a virus that lies dormant and occasinally gets re-activated.

Question: Confused about virus names - chicken pox (varicella zoster) and shingles (herpes zoster)? Okay, chicken pox is Varicella zoster. Shingles is Herpes zoster. Shingles is known to be the "grown up" chicken pox, and you can get it when the chicken pox virus you had as a kid (varicella zoster) becomes dormant and then returns as an adult. How does it change from varicella zoster to herpes zoster? What is bothering me about this is that it looks like they don't even belong to the same genus.

Answer: They are both caused by the same virus- varicella zoster virus (VSV) Varicella being chickenpox and shingles being zoster. It is from the herpes virus family. Its just nomenclature. See more on each infection here: http://www.examiner.com/x-7707-Tampa-Disease-Prevention-Examiner~y2009m5d28-Vaccine-preventable-diseases-chickenpox http://www.examiner.com/x-7707-Tampa-Disease-Prevention-Examiner~y2009m5d29-Vaccine-preventable-diseases-shingles

Question: HELP ME PLEASE!! varicella zoster? Varicella Zoster. What exactly is it (more of the structure) and what happens in it's Lytic and Lysogenic stages?

Answer: Varicella-zoster virus (VZV) is the cause of chickenpox and herpes zoster (also called shingles). Chickenpox follows initial exposure to the virus and is typically a relatively mild, self-limited childhood illness with a characteristic exanthem. Approximately 1 per 4000 children develops VZV encephalitis, an acute neurologic disorder with potentially severe complications. In addition, immunocompromised children (e.g., those receiving chemotherapy for leukemia or those with advanced HIV infection) can develop disseminated VZV infection, a potentially fatal complication. After primary infection, VZV remains dormant in sensory nerve roots for life. Upon reactivation, the virus migrates down the sensory nerve to the skin, causing the characteristic painful dermatomal rash. After resolution, many individuals continue to experience pain in the distribution of the rash (postherpetic neuralgia). In addition, reactivation of VZV infection can cause a spectrum of atypical presentations, ranging from self-limited radicular pain without rash to spinal cord disease with weakness. Pathophysiology: The host immunologic mechanisms suppress replication of the virus. Reactivation can occur if host immune mechanisms are compromised. This may be caused by medications, illness, malnutrition, or by the natural decline in immune function with aging. Upon reactivation, the virus migrates along sensory nerves and produces sensory loss, pain, and other neurologic complications. If motor nerve roots are also involved, weakness can develop in addition to sensory changes. Leptomeningeal involvement is rare but may develop when the ophthalmic branch of the trigeminal nerve is involved. Lytic cycle = the cycle of the viral infection, replication, and destruction Lysogenic cycle = the viral genome replicates without destroying the host cell. During an infection, some viruses stay inside the cells but do not make new viruses. Instead of producing virus particles, the viral gene is inserted into the host chromosome and is called a provirus. Whenever the cell divides, the provirus also divides, resulting in two infected host cells. In some lysogenic viruses, change in the enviroment can cause the provirus to begin the lytic cycle, which means the destruction of the host cell.

Question: antibodies for varicella zoster IgG - positive and varicella zoster IgM negative means immunity for shingles?

Answer: I don't think so. Varicella and Varicella Zoster are the same virus with different names. Shingles is endogenous, meaning if you had chicken pox, the virus stays there for life and can later crop up as shingles. If you have IgG positive, you're not immune, as far as I know.

Question: I am varicella Zoster (Igc) positive, what does this mean?

Answer: Varicella zoster virus is known by many names, including: chickenpox virus, varicella virus, zoster virus, and human herpes virus type 3 (HHV-3). VZV is closely related to the herpes simplex viruses (HSV), sharing much genome homology. A live attenuated VZV Oka/Merck strain vaccine is available and is marketed in the United States under the trade name Varivax. It was developed by Merck, Sharp & Dohme in the 1980s from the Oka strain virus isolated and attenuated by Michiaki Takahashi and colleagues in the 1970s. It was submitted to the U.S. Food and Drug Administration for approval in 1990 and was approved in 1995. Since then, it has been added to the recommended vaccination schedules for children in Australia, the United States, and many other countries.

Question: Can anyone interpret varicella zoster lab results? I got this test done among other tests to identify any fertility problems. My value was 2.86, but I have no clue what this means. Anyone knows how to interpret this? Thanks!! This is exactly what it said: Your Result VARICELLA ZOSTER VIRUS IGG, EIA 2.86

Answer: That means that you had previous chicken pox infection. Your antibody (IgG) will never turn negative. Varicella belongs to the herpes virus family. Once you have it....you will have it for life! Beware.....you might get shingles in the future.

Question: Varicella ZOSTER?? What is this and what does it mean if a pregnant woman's urine or blood tests..? detected this ?????

Answer: Varicella virus, zoster virus, human herpes 3 (HHV-3), and Varicella Zoster Virus (VZV) all refer to the same viral pathogen. The disease caused by this pathogen is called chickenpox or Varicella disease during the initial infection. A reactivation of the infection is commonly called shingles, herpes zoster or simply zoster.

Question: What is Varicella Zoster Virus?

Answer: The varicella zoster virus (VZV), also known as human herpes virus 3 (HHV-3), is one of the eight herpes viruses known to affect humans (and other vertebrates). Primary VZV infection results in chickenpox (varicella), which may rarely result in complications including VZV encephalitis or pneumonia. Even when clinical symptoms of varicella have resolved, VZV remains dormant in the nervous system of the host in the trigeminal and dorsal root ganglia. In about 10-20% of cases, VZV reactivates later in life to produce herpes zoster (shingles) and its associated sequelae including: post-herpetic neuralgia, zoster multiplex, myelitis, herpes ophthalmicus, or zoster sine herpete. VZV is closely related to the herpes simplex viruses (HSV), sharing much genome homology. The known envelope glycoproteins (gB, gC, gE, gH, gI, gK, gL) correspond with those in HSV, however there is not equivalent of HSV gD. VZV virons are spherical and 150-200 nm in diameter. Its lipid envelope encloses the nucleocapsid of 162 capsomeres arranged in a hexagonal form. Its DNA is a single linear, double strand molecule, 125,000 nt long. The virus is very susceptible to disinfectants, notably sodium hypochlorite. Within the body it can be treated by a number of drugs and therapeutic agents including aciclovir, zoster-immune globulin (ZIG), and vidarabine. A live attenuated VZV Oka/Merck strain vaccine is available and is marketed under the trade name Varivax. It was developed by Merck, Sharp & Dohme in the 1980s from the Oka strain virus isolated and attenuated by Michiaki Takahashi and colleagues in the 1970s. It was submitted to the U.S. Food and Drug Administration for approval in 1990 and was approved in 1995. Since then, it has been added to the recommended vaccination schedules for children in Australia, the United States, and many other countries, causing controversy because it is only expected to be effective for about twenty years, leaving adults vulnerable to the most dangerous forms of infection by this virus, whereas getting normal chickenpox as a child typically leaves them immune for life.

Question: what does Zovirax varicella-zoster immune globin oatmeal bath preperation and acetaminophen ? what does all that do for chiken pox and what is the cause of chicken pox how does it efeect the immune responce \and can u give me the answers plz no websites

Answer: immune globulin may shorten the duration oatmeal bath means nothing cause is a virus acetamenophin helps with pain it does not do anything to the immune system. If one's immune system is compromised then this illness can be fatal it stays in the nerves to priginate again later in life called this time varicella zoster good luck

Question: varicella zoster virus? what is the shape and size of it and some interesting facts?

Answer: Shingles is a painful rash caused by the Varicella zoster virus (Herpes varicellae), which is the virus that causes chickenpox . Shingles occurs in people who have had chickenpox and is a reactivation of the dormant virus. Shingles often occurs many years after the initial chickenpox infection. Shingles is contagious and may itself cause chickenpox. However, contact with a person with shingles or chickenpox cannot cause shingles.

Question: what is a varicella-zoster virus?

Answer: It is the virus that causes chicken pox. RN