Get the facts on Cooley Anemia treatment, diagnosis, staging, causes, types, symptoms. Information and current news about clinical trials and trial-related data, Cooley Anemia prevention, screening, research, statistics and other Cooley Anemia related topics. We answer all your qestions about Cooley Anemia.
Question: Is cooley's anemia a single celled or chromosomal abnomality?
Answer: The wording of your question is a bit confusing.
Cooley's Anemia does not result from a chromosomal abnormality. The most obvious example of a condition resulting from a chromosomal abnormality would Down Syndrome.
I think you are incorrectly using the phrase "single celled".
Cooley's Anemia is the result of a mutation in a single gene, the HBB gene. The HBB, or hemoglobin beta gene, is located on chromosome 11.
Question: Have you ever heard of Cooley's Anemia? The doctor said I have to get a blood test to check my iron levels. Does this ring a bell for anybody?
Answer: It is also called Thalassemia. http://www.thalassemia.org
Question: who discovered Cooley's anemia??????
Answer: Cooley's anemia was named after the doctor who discovered it. You may want to check out this site.
For more information
Cooley's Anemia Foundation
129-09 26th Avenue, #203
Flushing, NY 11354
(800) 522-7222
(718) 321-2873
Question: How do Polypeptide Chains affect Thalassemia (Anemia...)? I am currently in grade 9 and doing a powerpoint project on a Blood Unit, more specifically an inherited disease called Thalassemia (more commonly known as Cooley's Anemia or just Anemia). I read somewhere that some kinds of Thalassemia are from Hemoglobin E or S combining with the Thalassemia. (Hb E mixing: called "E beta Thalassemia". Hb S mixing: called "Sickle beta Thalassemia")
(Hb=>Hemoglobin)
I then read up on what Hb E or S was, I found out there are other letters I do not remember that are called Polypeptide Globin Chains. I do not understand what these are or what they have in common with Thalassemia, and my best guess is that they are some type of protein attached to the Hb.
Please help me because I need help for this project and no sites have helped me so far.
Thank you very much!
PS: I LOVE SCIENCE (L)
Answer: try wikipedia. its great for info like this.
http://en.wikipedia.org/wiki/Hemoglobin
http://en.wikipedia.org/wiki/Thallassemi…
Firstly, you have to understand the basic structure of hemoglobin:
Its made up of a total of 4 polypeptide chains: heterotetramer, (αβ)2
so, each hemoglobin has 2 alpha and 2 beta chain polypeptides.
Thalassemia:
Basically, the excess of a certain polypeptide causes the thallasemia. An excess of Beta chain causes alpha thalassemia (there is a problem in making enough alpha chain polypetide).
An excess of Alpha chain causes Beta thalassemia (there is a problem in making enough beta chain polypeptide).
So, there is nothing wrong with the polypeptide chains but there is a differency the amount of the polypeptide chains.
This is different from something like sickle cell disease in which the polypeptide chains themselves are screwed up.
Question: Can someone answer this for me? I am looking for some information on Cooley's Anemia. Can someone tell me what Cooley's Anemia is and what are the syptoms of it?
Thank you.
Answer: Cooley's anemia is also called Beta Thalassemia. It is a rare and life threatening blood disorder that is inherited. Symptoms usually start around the age of 2 They will have dark urine, abnormal facial disorders and poor growth. It can be treated with bone marrow transplants. The cause is a missing gene which affects how the body makes hemoglobin Hope this helps.
