G6PD Deficiency

Question: my youngest son has G6PD deficiency. Is there any possibility that my other baby have same problem.? I'm pregnant and my baby is about 5 month old. Is there any possibility that my baby will get G6PD deficiency because my youngest son is having that problem now.

Answer: G6PD usually doesn't cause major problems for the people with it, but it can be passed on by either parent. The only way to know your child's potential risk for inheriting the disorder is to know which of you or if both of you carry the trait. Chances are one of you is probably also G6PD deficient, and don't even realize it. Since you have one child with the disorder, one of you at least carries it- and so every child you have is at risk to inherit it. There is nothing you can do to prevent it either way, nor predict how seriously it will affect the child until it is born. I'm sure the doctor treating your baby can explain things better for you, so you can better understand the problem. Just talk with your doctor or your baby's doctor, and get the answers you need.

Question: Does the G6PD deficiency contribute to difficulty in weightloss? If so, how can it be treated?

Answer: im sorry i don't but you can try in google

Question: Effect of G6PD Deficiency on Carbohydrate homeostasis? How does a deficiency in the G6PD enzyme affect the balance of carbohydrates in a cell?

Answer: lol, I know where you live and you are asking this for your SPA...

Question: is g6pd deficiency related to sickle cell disease? if it is so, what are the no no's for a sickle cell patient my nephew had beeen diagnosed with g6pd deficiency on his newborn screening. I heard this has got to do with sickle cell . How true? My concern is on the restrictions linked to this sickness, food restrictions, medicines, physical activities, daily routines. I heard sickle cell patients should be banned from things like flavia beans, airplane rides,etc.

Answer: G6PD is an enzyme that is crucial in RBC metabolism. G6PD ( Glucose-6-phosphate dehydrogenase) is a form of hemolytic anemia. People who lack G6PD can have episodes of hemolytic anemia from certain anti-malarial drugs or ingesting fava beans (favism). G6PD is transmitted by a mutant gene located on the X chromosome being expressed fully in males who iherit the mutant gene. Women only can demonstrate this disorder if they inherit the mutant gene on both sets of X chromosome. Example: Male - Xg6pd Y would inherit as opposed to an XY chromosome set up. Women = Xg6pd / Xg6pd would have full blown G6PD wheras a woman Xg6pd / X would have a double red cell population, some affected by G6PD disease some not. Sickle Cell Anemia is a hemolytic anemia, but is a Hemoglobinopathy. A hemoglobinopathy is when abnormal hemoglobins are synthesized. In the case of Sickle cell, Hemoglobin S is the main hemoglobin. Decreases in Oxygen, pH, and dehydration promote sickling. Albeit, the two conditions are related, but have different mechanisms.

Question: Can someone with a blood disorder g6pd deficiency go scuba diving? My brother wants to go scuba diving but my mum looked on the WEB and it said you can't is that true?? plz need answeres ASAP!!!!!!

Answer: Glucose-6-Phosphate Dehydrogenase(G6PD) deficiency is the most common human enzyme deficiency; an estimated 400 million people worldwide are affected by this enzymopathy (Scriver etal., 1995). One benefit of having G6PD deficiency is that it confers a resistance to malaria. G6PD deficiency is also sometimes referred to as favism since some G6PD deficient individuals are also allergic to fava beans. Individuals with reduced G6PD activity are at risk for several pathologies which can be potentially serious (even causing death) if they are not properly treated. The severity of the pathologies associated with G6PD deficiency has prompted researchers to study this condition. Since the discovery of G6PD deficiency in 1956, thousands of research papers have been published on various aspects of this genetic condition. About 10 percent of American black males have G6PD deficiency, as do a lesser percent of black females. G6PD deficiency is also increased in frequency in people of Mediterranean origin (including Italians, Greeks, Arabs, and Jews). G6PD deficiency is also known as "favism," since G6PD deficient individuals are also sometimes allergic to fava beans. G6PD deficiency is an allelic abnormality which is inherited in an X-linked recessive fashion. When someone has G6PD deficiency, complications can arise; hemolytic anemia and prolonged neonatal jaundice are the two major pathologies associated with G6PD deficiency. Both of these conditions are directly related to the inability of specific cell types to regenerate reduced nicotinamide adenine dinucleotide phosphate (NADPH); this reaction is normally catalyzed by the G6PD enzyme. A consequence of this is that G6PD deficient individuals are resistant to the malaria causing parasite. In G6PD deficient individuals, anemia is usually caused by certain oxidative drugs , infections, or fava beans. When any one of these agents, or their metabolites, enters a G6PD deficient red blood cell, hemoglobin becomes denatured, thus destroying its function as the principal oxygen carrying molecule. In addition to being susceptible to hemolytic anemia, G6PD deficient individuals are also predisposed to prolonged neonatal jaundice. This can be a potentially serious problem as it can cause severe neurological complications and even death. Several kinds of treatments can be utilized in treating the different clinical manifestations of G6PD deficiency. One treatment relies on preventative measures. Researchers are currently genetically engineering the fava bean so that the causative agents of the hemolysis will be eliminated; this will allow favic individuals to eat fava beans. Some environmental exposures are hazardous, before scuba diving, medical advice should be sought. Hope this helps Matador 89

Question: Do people with G6PD deficiency ever get back their enzymes when they grow older? Can the result be positive in an adolescent who tested negative at birth?

Answer: Yes but very little

Question: I need help on a science essay, and want to know how G6PD deficiency affects various things!? I want to know the classification of g6pd as a sugar, protein, or fat. information on the structure of the g6pd enzyme, identification on the substrate of g6pd information on the location of g6pd synthesis within the well explanation of the possible effects of g6pd deficiency on cellular respiration and carbohydrate homeostasis and the functioning of two organelles. PLEASE PLEASE HELP!!! i'm so confused, and none of this information is located on the internet!!

Answer: hahah i hate biology... youre screwed.... :P jk i hope someone knows the answer to that.

Question: Dye Decolourisation screening test for G6PD deficiency? Dye Decolourisation screening test for G6PD deficiency Discuss the principle of the following tests and what haemolytic anaemias can this help identify??? It is also known as Motulsky dye-decolouration test.

Answer: Diagnosis The diagnosis of G6PD deficiency is made by a quantitative spectrophotometric analysis or, more commonly, by a rapid fluorescent spot test detecting the generation of NADPH from NADP.7 The test is positive if the blood spot fails to fluoresce under ultraviolet light.8 In field research, where quick screening of a large number of patients is needed, other tests have been used; however, they require definitive testing to confirm an abnormal result.9,10 Tests based on polymerase chain reaction detect specific mutations and are used for population screening, family studies, or prenatal diagnosis. try also www.bioline.org.br/request?hg04008

Question: Can G6PD deficiency consider as a chronic disease?

Answer: well if it is a slow onset and never goes away, then yes, it can be chronic.. also, it can cause other chronic diseases to apppear.. http://www.aafp.org/afp/20051001/1277.html

Question: I have G6PD deficiency. Can I donate my blood to others?

Answer: Probably not. As you know, many drugs can cause your red blood cells to break down if you have G6PD deficiency. Because most patients who require blood transfusions are also receiving other medications, it would be too risky to administer blood that may undergo hemolysis and cause hyperbilirubinemia or splenomegaly or other complications.

Question: G6PD Deficiency? Hi I am G6PD deficiency and my daughter too. I don't know who on my family is g6pd either my Mom or my Dad. Could be one of them that I got it from? Thanks

Answer: it is an inherited condition that is found on the X chromosone. Either parent could have passed it to you . The only way to know is to have genetic tests ran. In the mean while take care of your self and your child to control it.

Question: hi i am a father for 3 month baby boy diagnosed as a G6PD Deficiency i need to know only the cure ? i need recommendation to a good Doctor for G6PD Deficiency in any part of the world . bless you all

Answer: G6PD deficiency is the most common known human enzyme disease, affecting 10% of the world's population. Treatment of G6PD deficiency involves discontinuing the offending drug or compound and treating any accompanying infection. Recovery is the rule. Sometimes blood transfusions are needed when the anemia is severe. http://www.medicinenet.com/g6pd_deficien… Under normal circumstances, G6PD deficiency usually does not cause problems for most children. However, it can become a problem when children develop an illness or infection; when they take certain medications, such as pain medicines, certain antibiotics, and drugs to treat malaria; or when they are exposed to other specific substances, such as mothballs or fava beans. All of these things increase the amount of oxidative stress on the body's red blood cells. Treating the symptoms associated with G6PD deficiency is usually as simple as removing the trigger - that is, treating your child's illness or infection or discontinuing the use of a certain drug. However, severe anemia may require treatment in the hospital, such as supportive care with oxygen and fluids, and sometimes a transfusion of healthy blood cells. In rare cases, the deficiency can lead to kidney failure or shock, requiring intensive care in the hospital until the child recovers. With the proper precautions, G6PD deficiency should not keep your child from living a healthy, active life. http://kidshealth.org/parent/general/ach…

Question: List of drugs/medicines not to be given to a person having G6PD deficiency?

Answer: Drugs: primaquine, salicylates (aspirin, Pepto-Bismol), sulfonamides, nitrofurans, phenacetin, some vitamin K derivatives, dapsone, phenazopyridine, nalidixic acid, methylene blue Other: naphthalene (moth balls). Food (only in some caucasians) fava beans.

Question: what is the food that should not taken by g6pd deficiency baby ? pls provide a better food list

Answer: I could find the foods to *avoid* for a g6pd deficiency baby: 4. Avoid ingestion of or exposure to the following food: FOOD AND DRINKS THAT MUST BE AVOIDED MGA PAGKAIN AT INUMIN NA DAPAT IWASAN Fava Beans - Dingdong nuts, Mr. Bean Redwine Legumes - Habitswelas, Garbanzos, Kadyos or Black Beans, Monggo Blueberry Soya Food - Taho, Tofu or Tokwa, Soy Sauce Tonic Water Bitter Melon or Ampalaya

Question: my 7 month old daugther has a G6PD deficiency, i'd like to know if there is a better formula milk for her?

Answer: You'd be better off asking a doctor then trusting random people you don't know on yahoo answers.

Question: does the prune juice cause harm to a Glucose-6-phosphate dehydrogenase deficiency(g6pd) positive? i have a neighbor whose baby is g6pd positive and when the baby drank prune juice his face turn black and is coughing badly...

Answer: No, drinking prune juice will hyper ventilate the circular quadrants of the upper depository receptacle, and if not closely watched, could cause a person to become hypo glycemic, a diabetic quadro placegic, over and over again. It happened to a friend of mine and now he is a she.