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Parkinsonism
Get the facts on Parkinsonism treatment, diagnosis, staging, causes, types, symptoms. Information and current news about clinical trials and trial-related data, Parkinsonism prevention, screening, research, statistics and other Parkinsonism related topics. We answer all your qestions about Parkinsonism.
Question: Does Dr A S Hegde, Neurosurgeon, Bangalore have parkinsonism and not do operation? My mother was admitted & investigated at Rajkot, Gujarat.
She is having (anterior communicating artery) hemorrhage and subarachnoid bleed.
I heard from other doctors that Dr AS Hegde operates on subarachnoid bleed cases. But I heard that he is not operating now because of health problem-parkinsonism.
Can you please clarify and let me know if it is true?
Answer: Oops, I think this is a dangerous question and have legal implication.
Question: Is it true that longterm use of Lamotrigine could lead to side effects such as the symptoms of Parkinsonism? what are the side effects of levaticitapem?
Answer: Lamotrigine has been tried as a treatment FOR Parkinson's, without much concrete success, though the findings did support the need for larger studies of Lamotrigine treatment for Parkinsonism...but there is no data suggesting that use of Lamotrigine will actually lead TO Parkinsons.
Before Lamotrigine is prescribed, the patient should have a thorough medical evaluation, including blood and urine tests, to rule out any medical condition, such as thyroid disorders, that may cause or exacerbate mood disorders or otherwise interact with the drug therapy.
Side effects that affected 10% or more of the 711 people taking the drug during clinical trials and the frequency of those side effects in the 419 people treated with placebo in those trials include the following adverse reactions:
Dizziness
Headache
Double Vision
Unsteadiness
Nausea
Blurred Vision
Sleepiness
Rash
Vomiting
There are also reports of agitation, anxiety, concentration problems, confusion, depression, emotional instability, irritability, and mania in those using Lamotrigine.
The most noticeable side effect of Lamotrigine, even causing people to discontinue it in some cases, is a rash. In rare cases, the rash was shown to be life threatening in some patients so it's important to get it checked out.
Common symptoms of Parkinson's include:
Tremor, usually in the hand or foot on one side of the body
Rigidity and stiffness or inflexibility of the muscles
Bradykinesia, which is exhibited by slow and/or incomplete movement; the person often has difficulty initiating movements and suddenly stops ongoing movement...people who have bradykinesia may walk with short, shuffling steps or affect the facial muscles, reducing a person's range of facial expressions and resulting in a "mask-like" appearance
Postural instability or impaired balance and coordination
Speech changes
Difficulty swallowing
Pain
Dementia or confusion
Sleep disturbances
Depression
Memory difficulties and slowed thinking
Sexual dysfunction
Hope that helps somewhat.
Question: Can a person who is normal suddenly develop parkinson's or parkinsonism just coz of stress or lack of sleep? The person is currently have shaking tremors in hands and little stiffness in the back and neck, the eyes suffer from burning sensation and pain and the person also has sinus problems. Talks less and eats normally with a normal appetite and weight. The person wears glasses and has a number in the left eye for distant vision..
Answer: One does not develop parkinsons just because a lack of sleep or an increase in stress -- if that were the case, the majority of the population would have parkinsons.
It is possible to have parkinsons and not have very many manifested symptoms -- these symptoms can become more prevalent when stressed.
Question: Can Parkinsonism result from alcohol abuse?
Answer: The shaking isn't from Parkinson's. It's from alcohol withdrawal.
Question: Preventive measures on a patient diagnosed with viral encephalitis to second degree parkinsonism? aside from the question above.
with regards to the behaviour? how could you help the a person with such diagnosis? - physically, mentally and emotionally
or the individuals around him must adjust for him?
asocial behaviour/speech problems? i know this may occur on the patient later on - is constant acquaintances with other individuals helps lower the asocial aspect? or is it just on the state of the mind that hinders the patient on recovering for himself?
thank you!
Answer: chek www.planetayurveda.com and write to drvikramchauhan@yahoo.com for free ayurvedic consultation
Question: is there any website regarding parkinsonism and videos on the same. and i need to know clear diagnosis?
Answer: 1. parkinson syndrome
2. i'm pretty sure a doctor can diagnose it
3. ever hear of google?
Question: what are the symptoms of parkinson? medically known as parkinsonism? one md diagnosed me as having parkinsonism, another specailist said it was a misdiagnosis and had me discontinue use of the prescribed drugs following two visits a month apart. I understand that it is difficult to diagnose and am worried about the uncertainty concerning the diagnosis. Both specialists (neurologists) inspected the same sleep study results. I have no tremble of my hands and my handwriting has not diminished in size. My unsteadiness is due to the calcification of the soft tissue following a total right hip replacement 11 months ago.(april 5 2005) I am almost 77 (july 2006) and otherwise in satisfactory health even though I have had one kidney excised about 5 years ago. A younger brother died at 75 from parkinson related heslth problems.
Thank you for your considered comments.( sleeping many hours a day I consider enjoyable as I have very little work in my university career. mostly treduced to writing and editing. Seamus
Answer: Parkinson's disease sometimes is described as early, moderate, or advanced.
Early disease describes the stage when a person has a mild tremor or stiffness but is able to continue work or other normal daily activities. This often refers to a person who has been newly diagnosed with Parkinson's disease.
Moderate disease describes the stage when a person begins to experience limited movement. A person with moderate Parkinson's disease may have a mild to moderate tremor with slow movement.
Advanced disease describes the stage when a person is significantly limited in his or her activity, despite treatment. Daily changes in symptoms, medication side effects that limit treatment, and loss of independence in activities of daily living are common. A person with advanced Parkinson's disease may have significant changes in posture and movement, speech problems, and frequent changes in movement.
Parkinson's disease may also be described by five stages:
Stage I (mild or early disease): Symptoms affect only one side of the body.
Stage II: Both sides of the body are affected, but posture remains normal.
Stage III (moderate disease): Both sides of the body are affected, and there is mild imbalance during standing or walking. However, the person remains independent.
Stage IV (advanced disease): Both sides of the body are affected, and there is disabling instability while standing or walking. The person in this stage requires substantial help.
Stage V: Severe, fully developed disease is present. The person is restricted to a bed or chair.
Question: Drugs for anti-parkinsonism? does anyone know a site that gives the brand name and generic names aof drugs that can be used for anti-parkinsonism. i have been trying hard to find one but i couldent there is this site that gave me one drug Akineton(piperadon) but unfortunately i need 5. any help will do. please
Answer: Here's five for you:
Brand name - Generic name
Sinemet - carbidopa/levodopa
Mirapex - pramipexole
Requip - ropinirole
Comtan - entacapone
Eldepryl - selegiline
Question: My father has Parkinsonism. Is it curable ? If so, how ? He has been suffering for 12 years !
Answer: Parkinsons disease?? is so, no, as of yet there is no cure for Parkinsons, sorry
Question: juvenile parkinsonism? At night sometimes I get spasms, they only last a few seconds and they're not bad or anything; just before I have it, I see the ground, and then it's almost as if I'm falling onto the ground, it kind of feels like I'm lifting my knees up. It's hard to explain. Anyway, my mum was watching a tv programme about dreams, and it was talking about REM sleep disorder, and how it can involve spasms, and also how it can be a symptom of Parkinson's disease. My grandfather had parkinson's for ten years, it was horrible, he got worse day by day by day, in the end he couldn't even open his mouth or walk, or move from his chair without assistance from two carers. I'm thirteen and probably being really paranoid but is there a chance I have juvenile parkinsonism? I just need to know, I get extremely worried, it's silly really.
Anyone? Please.
Thanks Tinfoil_tiaras :)
I can be very... paranoid at times.
Thankyou x
Answer: No. To me this sounds like it is probably just myoclonic jerks - involuntary muscle contractions. To get this when falling asleep is completely normal but people with various neurological disorders including Parkinson's disease can get similar but more severe spasms at any time - ie during the day, when they are wide-awake.
Just to give you a bit more info, muscle spasms are only a feature of Parkinson's disease later on in the disease. The three main features of Parkinson's are tremors, slowing of movement and muscle rigidity.
So you definitely don't have that, anyway and the chances are it's nothing to worry about. But if you're concerned speak to your mum and a doctor could see you just in case to take a few more details from you.
Question: Can malabsorption syndrome cause Parkinson's disease or parkinsonism?
Answer: parkinsonism is due to deficiency in l-dopa levels ins the basal ganglia ,its not related to malabsorption ,its can be due to major tranquilizers side effects and called parkinsonism ,or parkinson disease which arises de novo
Question: How best to deal with Parkinsonism? Non progressive atypical parkinsonism. Hand writing has become smaller, no tremors, mainly rigidity predominant with vertigo. This has been static since last 6 months. He has been recently, that is a week back put on ROPARK that is Ropinirazole. His MRI and MRA has been reported as normal.
Answer: Hi Harsha
Here are some ideas on how to help the healing process.
Cause
Although the cause is unknown, an imbalance of two brain chemicals, dopamine and acetylcholine, seems to be involved. A deficiency of dopamine in the brain can be due to underlying nutritional deficiencies, cerebral vascular disease (blockage of blood vessels in brain), side effects of anti-psychotic drugs, carbon monoxide poisoning, abuse of certain designer drugs, and a rare infection (encephalitis lethargica).
Parkinson's disease has been associated with toxic buildup of heavy metals in the body, especially mercury from dental amalgams. To slow the progression of Parkinson's amalgam fillings should be replaced, followed by a detoxification program.
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Natural Cures
Note: Left untreated, over time (usually years) Parkinson's can lead to severe incapacitation. Treatment with complicated drug combinations and mobility exercises can reduce the progression and severity of the disease.
Levodopa and Sinemet are the two most commonly used drugs for treating Parkinson's disease, but Levodopa is made ineffective if taken with vitamin B6. (Sinemet does not have this problem.) Using vitamin B6 alone can be just as effective in some individuals in the initial stages of the disease. Levodopa should also be taken away from protein meals, which decrease its effectiveness.
Diet: Eat an organic, whole foods diet with raw foods (50% to 75%), emphasizing dark green leafy vegetables, rutabagas, sprouts, sesame seeds, and sesame butter. Also drink plenty of pure, filtered water.
People using the drug levodopa should avoid or minimize their intake of foods that are rich in vitamin B6--whole grains, oats, raw nuts (especially peanuts), bananas, potatoes, liver, and fish.
Herbs: Passionflower can enhance the positive effects of the drug L-dopa (levodopa), producing a greater reduction in tremor. The Ayurvedic herb Mucuna pruriens, a natural form of levadopa, can also be helpful.
Nutritional Supplementation: Assessment of individual amino acids is important. Consult an orthomolecular doctor. Other useful nutrients include GABA, calcium, and magnesium, vitamin B complex (taken away from Levodopa), lecithin vitamin C, vitamin E, evening primrose oil, multivitamin/mineral complex, and DHEA (a steroid hormone produced by the adrenal glands). The coenzyme nicotinamide adenine dinucleotide (NADH) (25-50 mg per) day administered intravenously has also been shown to produce a beneficial effect in patients with Parkinson's. Selenium is also recommended for its ability to detoxify mercury poisoning.
Alternative Professional Care
If your symptoms persist despite the above measures, seek the help of a qualified health professional. The following professional care therapies have all been shown to be useful for treating Parkinson's Disease: Cell Therapy (Stem Cell Therapy), Chelation Therapy (extremely important for detoxifying from heavy metal poisoning), Craniosacral Therapy, Detoxification Therapy, Holistic Dentistry, Light Therapy, Magnetic Field Therapy, Natural Hormone Replacement Therapy, Naturopathic Medicine, Orthomolecular Therapy, and Traditional Chinese Medicine.
Best of health to you.
Cheers
Question: Could anybody give me advice on this issue? Could anybody give me advice on this issue?
Does my daughter, a young girl with a neurodegenerative disease (Parkinsonism...) who is just 18 have any chance to find a boyfriend as a date?
Thanks in advance.
She's also good-looking, so there's still some hope. Thanks all.
Answer: for everyone there is someone.
dont you let her give up.
everyone has someone to love, and even if a boy is not in her plans, i know the lord will provide her with all the love she needs.
if it is in her deepest desires to have a man to love her, im sure god has a plan to fulfill her desires. you are her mother! its your job to give her faith and hope! remember that the second you give up, shell come tumbling down with you. i wish you the best.
psalms 139: 17-18
Question: what is "parkinsonism" ? and what are it's symptoms?
Answer: Parkinson's disease is a very serious illness caused by the progressive deterioration of the nervous system or by destruction of connections in the brain. Patients gradually lose the ability to control their muscles, lose the ability to hold their limbs still, lose their balance, lose their strength. They often have tremors and eventually end up in wheelchairs essentially paralyzed, unable to control bladder or bowels, unable to do anything for themselves at all. It's like being trapped inside a non-functioning body, but being aware of what's going on, quite a terrible way to go. Scientists are attempting to develop treatments with stem-cells by transplanting new neurons (a type of brain cell) into affected areas of the brain, with some limited success. There are also drugs or medications but these have very strong side effects including severe weight loss. Patients tend to live 5 to 10 years after diagnosis before diseases like pneumonia tend to carry them off because they can't fight off communicable diseases like this very well. But the new research is beginning to show promise as DNA and RNA research is narrowing down the real causes. This will show us where to look for a real cure, not just treatment of symptoms.
Question: high serum pyruvate level and parkinsonism? young woman with high serum pyruvate and parkinsonian features, extensive neuroimaging and metabolic work up has revealed normal results
Answer: Hi Cogitum. Arsenic poisoning can lead to abnormal accumulation of pyruvate. "Arsenite (the trivalent form of arsenic) forms a stable complex with thiol (-SH) groups of lipoic acid, making that compound unavailable to serve as a coenzyme. When it (arsenite) binds to lipoic acid in the pyruvate dehydrogenase complex, pyruvate (and consequently lactate) accumulate. ...this particularly affects the brain, causing neurologic disturbances and death."
This is taken directly from "Lippincott's Illustrated Reviews; Biochemistry, 3rd edition by Champe and Harvey and published in 2005.
In plain english, the textbook is saying that arsenic (a common heavy metal that is very toxic) prevents the enzyme that converts pyruvate into acetyl coA from doing just that. The result is a buildup of pyruvate and lactate in the blood and a significant loss of energy production by the body. The net result of all this is brain injury.
I encourage you to share this with your doctors. Best wishes and good luck!
Question: Balance and coordination problems - what else could it be? I suffer from balance anc coordination problems. The symptoms get much worse with expectation of a problem. For example if I think I am going to be faced with a crowd of people. They are also much worse when I run into some unexpected situation or person. I have a slight left hand tremor and have been taking medication for Parkinsonism for some time now. I do not have any real rigidity anymore. I do not believe it is Parkinson's disease. What else could it be?
Answer: Hello Ronnie S.
A fairly complex problem (associated with many causes) but it is very interesting that your imbalance is associated with social situations.
My best guess is that you are being treated with an L-dopa type of medication and this/these meds commonly affect a systems that might cause your instability, directly or indirectly. The neuro chemical responce to social apprehension would make these more pronounced.
L-dopa causes "postural blood pressure drops" in 30 % of people especially if you are a bit dehydrated..........Are your symptoms worse if you stand up rapidly ?..Have a thorough b/p check in lying, sitting standing positions.
Secondarily, L-Dopa may cause stimulation of the heart (increased rate or rythm disturbances): this can be aggravated by social situations too. Have you had an electrocardiogram recently ?
Are you taking a multivitamin ? Vit B-6 causes irradic absorbtion of l-dopa...avoid B-6.
These symptoms can be treated with a "beta blocker" ie Inderal.
If you take Sinemet, you can ask your physician to adjust the mixtue of Cardio dopa: Cardio dopa influences the effects of L-dopa.
What you are expeiencing sounds like "stage fright " like, and L-dopa will make it worse.
Hope this helps.
Be well
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