ask our doctors


Get the facts on Macrocytosis treatment, diagnosis, staging, causes, types, symptoms. Information and current news about clinical trials and trial-related data, Macrocytosis prevention, screening, research, statistics and other Macrocytosis related topics. We answer all your qestions about Macrocytosis.

Question: Can you expalin to me what macrocytosis is all about? Is it dangerous? The Dr thinks my husband has it. I do know it has something to do with his kidneys. But that's all I know. I've tried looking it up on the web but the language is way over my head. So could someone please explain it in laymans terms?

Answer: Macrocytosis is the enlargement of red blood cells with near-constant haemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories). this means larger than normal red blood cells [edit] Causes Most commonly (especially when the increase in size is mild, and just above normal range) the etiology is bone marrow dysplasia primary to alcohol abuse. Other causes may include: Megaloblastosis (Vitamin B12 or folate deficiency; or DNA synthesis-inbiting drugs) hypothyroidism reticulocytosis (commonly from hemolysis or a recent history of blood loss). liver disease myeloproliferative disease [edit] Complications No complications arise from macrocytosis itself and a prognosis will be determined from its aetiology Generally speaking, macrocytosis affects the kidneys because the enlarged cells sort of "clog" up the tubes so to speak inside the kidneys. Depending on the severity of the macrocytosis, it can be treated with B-12 supplements or injections. If you have further questions feel free to contact me.

Macrocytosis News