Factor VIII

Question: Factor VIII? What is a normal Factor VIII level? I have Von Willebrands disease, and my level is normally around 50% but now it's gone down to about 30%. Is this cause for concern? My hematologist is going to repeat my blood work, but not until next month.

Answer: Patients with vWD normally require no regular treatment, although they are always at increased risk for bleeding. Prophylactic treatment is sometimes given for patients with vWD who are scheduled for surgery. They can be treated with human derived factor VIII with vWF(antihemophilic factor, more commonly known as Humate-P®) Mild cases of vWD can be trialled on desmopressin ( Stimate®), which works by raising the patient's own plasma levels of vWF by inducing release of vWF stored Normal results vary between labs, but in general, a result between 50% and 200% is considered normal. plus u do vwf factor level..they work together to stop bleeding........ Expectations Women who have this condition generally do not experience excessive bleeding during childbirth. Since this disease is inherited, genetic counseling may be recommended for parents. Complications Post-operative hemorrhage (bleeding) may occur. If you have von Willebrand disease, do not take nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin or ibuprofen without talking to your health care provider. Calling your health care provider Call your health care provider if bleeding occurs without reason. If you have von Willebrand disease and are scheduled for surgery or are in an accident, be sure you or your family notify the health care providers about your condition. so i think ur condition needs further tests or u dont know whether vwf was done....the only problem u may have is excess bleeding.....which is mild in vwf disease

Question: What test can be done for Thrombophilia factor VIII? -If a mother has it<leg amputated,triple heart bypass etc etc> how can you find out if it is heriditary. Also at what age would warfrain be taken if thrombophilla factor 8 was diagnosed?

Answer: This page will give you all your answers: http://peir.path.uab.edu/coag/article_20… I don't think they would start you on warfarin without you having a major thrombolic event.

Question: Which is associated with the inability to produce factor VIII in the blood? _____20. Which is associated with the inability to produce factor VIII in the blood? a) male pattern baldness b) sickle-cell disease c) color blindness d) hemophilia e) Duchenne muscular dystrophy

Answer: factor VIII (one of the proteins important for coagulation) Coagulation is a complex process by which blood forms solid clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel) whereby a damaged blood vessel wall is covered by a platelet- and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Haemophilia or hemophilia is the name of several hereditary genetic illnesses that impair the body's ability to control bleeding

Question: Does anybody know where can i get the information about the coagulation factor VIII and IX? I need to know how they work in our body, and how the missing of them causes haemophilia.

Answer: Please see the webpages for more details on Hemophilia A and Hemophilia B.

Question: what is Factor VIII and its complications? Can the person died for it? my doctor told I have 50 on the results of the Factor VIII and the lowest range is 60.

Answer: Hemophilia A It is caused by a deficient activity of plasma protein factor VIII, which affects the clotting property of blood. http://www.healthcentral.com/mhc/top/000… NHF | Bleeding Disorders Information Center | Hemophilia A BLEEDING DISORDERS INFO CENTER > TYPES > HEMOPHILIA A Hemophilia A (Factor VIII Deficiency) What Is It? ... Complications . Chronic joint http://www.hemophilia.org/bdi/bdi_types1… Low Molecular Weight Peptides Restore the Procoagulant Activity of... Low Molecular Weight Peptides Restore the Procoagulant Activity of Factor VIII in the Presence of ... developed to circumvent complications arising http://www.jbc.org/cgi/content/full/277/… NEJM -- Nonviral Transfer of the Gene Encoding Coagulation Factor... No long-term complications developed, and no inhibitors of factor VIII were detected. In four of the six patients, plasma levels of factor VIII... http://content.nejm.org/cgi/content/shor… HIV & AIDS - Factor VIII, HIV and AIDS in Haemophiliacs: An analysis ...and sufficient for the development of the clinical AID syndrome. Factor VIII and HIV ... Since factor VIII is made from plasma, as a first step... http://www.virusmyth.net/aids/data/ephem… Formation of Antibodies to Factor VIII in Patients with Hemophilia A Table 1. Interferon Therapy and Incidence of Development of Antibodies to Factor VIII ... are transient and produce no clinical complications; http://www.annals.org/cgi/content/full/1… Bioengineering of coagulation factor VIII for improved secretion --... Factor VIII activity and antigen analysis... http://www.bloodjournal.org/cgi/content/… Prevention and treatment of factor VIII inhibitors in murine... ...time as they received the first of 3 additional factor VIII injections. While many mice died of bleeding complications during this experiment... http://www.bloodjournal.org/cgi/content/… eMedicine - Factor VIII : Article by Rajalaxmi McKenna, MD, FACP Factor VIII Last Updated: July 19, 2005 ... Rate this Article ... Email to a Colleague ... Get CME/CE for article ... See Complications for a http://www.emedicine.com/MED/topic981.ht… Elevated Factor VIII or D-Dimer Predicts Poor Prognosis in Children... Elevated Factor VIII or D-Dimer Predicts Poor Prognosis in Children With Thrombosis ... The prevention of thrombosis-related complications in http://www.medscape.com/viewarticle/4889…

Question: Recombinant factor VIII is a replacement product prepared by,,,? I kinda need help with finding out what recombinant factor VIII for blood is. i have a huge test tomorrow on hemophilia and that is one of the review questions i don't know about. can ya help?

Answer: Hemophilia Village | Health Care... ... decision when choosing a recombinant factor VIII replacement product for your patient with hemophilia A, we've included... www.hemophiliavillage.com/hcp_refacto_… Cecil Textbook of Medicine : /> ... 000, depending primarily on the choice of replacement product (e. ... Recombinant factor VIII and IX concentrates (see... www.merckmedicus.com/ppdocs/us/common/… Should I Have Regularly Scheduled or... Hemophilia A is caused by a deficiency of active clotting factor VIII (8) ... It is less expensive than donated and... seton.net/health_a_to_z/health_library…

Question: Do you know any website online that ships you factor VIII...it's a treatment for hemophilia!!!? plz and thank u!!! factor VIII only!!

Answer: no but GL it is funny i thought people wouldnt be here to answer today is christmas go away! happy christmas

Question: why plasmapheresis is use to remove factor VIII,could this be use in a procoagulable state?

Answer: The process of plasma pheresis is similar to dialysis. The blood is removed and the blood components separated and all of the components are returned to the donor except plasma. Once the plasma is removed from the donor it is processed to remove only the Factor VIII. It takes the blood of many donors to make Factor VIII products. Now a common way to make Factor VIII is with recombinant DNA - reducing the risk to the recipient of blood borne diseases. It is possible to use plasma pheresis to remove some abnormal proteins from a patient - like someone with Multiple Myeloma - but to use this to reduce the amount of Factor VIII because they have a procoagulable state would not be very practical. There are a lot more treatments and options - Heparin, Coumadin, Aspirin, Plavix.

Question: what is a normal factor viii level?

Answer: We don't normally measure Factor VIII levels. Usually we test the intrinsic clotting pathway by measureing APTT - Activated Partial Thromboplastin Time. Where I've looked it seems that they express Factor VIII levels as a %age of normal. Barely noticeable Hemophilia at 10-30%, mild at 5-10% of normal levels, and severe at <=1% of normal Factor VIII levels. It is possible to measure them, but it is costly and usually only in the realm of the Hematologist specialists.

Question: place online that sells factor VIII? plz help!!!!!

Answer: I doubt any online places have the stuff, but regardless: Don't risk buying factor VIII online! Get it from a properly licensed pharmacy under the direction of your physician! If you cannot afford your medicine ask your physician about assistance programs. You never know what you're getting online. You could bleed to death or die from an infection caused by a contaminated counterfeit product. Best Wishes