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Sebaceous Carcinoma

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Question: As a Physician I'm dealing with a rare kind of cancer, i.e. sebaceous carcinoma of the penis and need advice Sebaceous corcinoma of the penis is so rare that I could't find but an article in the "Archives of Dermatology", vol.117/1981. Can anyone help me either with an updated bibliography or sharing with me her/his experience ? I thank you in advance

Answer: There are two older citations in PubMed but only one has an abstract available. Sorry but there is not much info here. Cancer. 1985 Sep 1;56(5):1163-72.Links Adnexal carcinomas of the skin. II. Extraocular sebaceous carcinomas.Wick MR, Goellner JR, Wolfe JT 3rd, Su WP. Extraocular sebaceous carcinomas are uncommonly seen neoplasms, and have been confused in the past with basal cell carcinomas showing sebaceous differentiation. In contrast to the latter tumors, however, sebaceous carcinomas have a distinct risk of aggressive behavior. This study presents clinicopathologic data on five cases of sebaceous carcinoma arising in cutaneous locations outside of the ocular adnexae. Four of five patients were men, and the average age at diagnosis was 63 years. Three tumors occurred on the face, one arose in the skin of the neck, and another occurred on the penis, an anatomic site that is extremely rare for sebaceous carcinoma. Three tumors metastasized, and two patients died of tumor or with residual tumor growth. In light of this behavior, the premise that extraocular sebaceous carcinomas rarely spread to distant sites may need reexamination. PMID: 4016704 These articles might be helpful. http://www.emedicine.com/derm/topic394.h… http://www.emedicine.com/derm/topic275.h… http://www.medscape.com/viewarticle/4968… good luck with this patient


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