Lupus Erythematosus Drug Induced

Question: Can "drug-induced lupus erythematosus" be the reason behind the death of Michael Jackson? Since as it was known he had two severe illnesses "vitiligo" and "lupus".

Answer: A number of people have died from it, so why not? I'm not saying that it really is the cause, but it's possible.

Question: This is a lot to ask, I know. But if someone could review my APA paper I would GREATLY appreciate it. ? I think my greatest problem is with grammer errors and my in-text citations. Also, all of those citations that repeat themselves look funny to me. They can't be right? Can they? I'm also confused with secondary citations. I think they're a no no but I can't get a clear answer on what they are. Here's the paper. Please kindly review if you'd like. I'd love yah for it. Kisses Mandi (Title page not included) Introduction Lupus is an autoimmune disease that permits the affected body to build antibodies to attack its own cells as if they were foreign. There are three main types of lupus. They are discoid, drug induced, and Systemic lupus erythematosus (Encyclopedia Britannica, 2009). Doctors must be careful in diagnosing lupus since it can easily be confused with other diseases (Rahman & Isenberg, 2008). Lupus is capable of attacking any part of the body but for the most part it mainly affects the skin, kidneys, joints, heart, gastrointestinal tract, and serous membranes (Encyclopedia Britannica, 2009). The cause of Lupus is currently unknown. Lupus truly is a sickness of mystery since the cause and cure have currently been unidentified. However, there are known genetic (Encyclopedia Britannica, 2009) and environmental (Rahman & Isenberg, 2008) aspects that have been known to trigger this illness. On an inspiring note, there is presently a study being conducted with mice in search for the cure of lupus. Discussion Lupus is an autoimmune disease that is known to be a chronic (continuous or reoccurring) inflammatory illness that has the ability to attack any region of the body (Encyclopedia Britannica, 2009). The symptoms of the disease are painful or swollen joints and muscle pain, unexplained fever, red rashes, chest pain when breathing deeply, loss of hair, pale or purple fingers or toes from cold or stress (also known as Raynaud's phenomenon), sensitivity to the sun swelling in legs or around eyes, mouth ulcers, swollen glands and extreme fatigue (WebMD, 2008). Those that suffer from lupus may never have the same symptoms as another person with the disease (Encyclopedia Britannica, 2009). However, the most common areas of the body affected are the skin, kidneys, joints, heart, gastrointestinal tract, and serous membranes (Encyclopedia Britannica, 2009).. Also in most cases in order for a doctor to diagnose lupus the patient must illustrate at least four (Encyclopedia Britannica, 2009) of the listed symptoms. The actual cause of the disease is unknown. However, there are genetic and environmental characteristics that could trigger lupus to develop. Many patients that suffer from lupus have a genetic association with the disease (Encyclopedia Britannica, 2009). Lupus could be the result of mutated genes of interferon and the genes that play vital roles in regulating the immune response (Encyclopedia Britannica, 2009). If a patient has a genetic link to lupus there are also environmental aspects that could trigger lupus. They are infection, ultraviolet light, certain drugs like; procainamide, hydralazine, and quinidine (Rahman & Isenberg, 2008), and extreme stress (Encyclopedia Britannica, 2009). Factors that potentially contribute to the progression of lupus are interleukins and interferons (immune molecules). Interleukins and interferons have been shown to control the autoantibody release in response to certain bodily stimuli (Encyclopedia Britannica, 2009). Lupus commonly affects women, African Americans, and Asians more than any other group (Rahman & Isenberg, 2008). Since 90% of all patients with lupus are female, women between the ages of 15-50 should be tested for lupus if they portray at least one of the symptoms (Rahman & Isenberg, 2008). Also, there is an increased risk of lupus in people who already have the Epstein-Barr virus. (Rahman & Isenberg, 2008) The healthy immune system’s mission is to protect the body from infections and foreign objects within the body. When the immune system is working properly it will recognize the foreign bacteria, virus, or objects as non-self. Upon recognition that something does not belong, it will build antibodies against the unwanted agent, attack and destroy it (Marieb, 2009, p. 408 & 410). However, the activities of the immune system are much different when the body is affected with lupus. Instead of the body producing antibodies against foreign bacterial that do not belong, the immune system will produce an autoantibody that attacks the body’s own cells and tissues. The reason for this is because they can not recognize their own cells or tissue as self. When an autoantibody attack occurs, the autoantibodies will attach themselves to various tissues and cells (Rahman & Isenberg, 2008). When this happens the body’s inflammatory response occurs. The same thing happens when we have been hurt and the tissue has truly been damaged. There are a few different ways Lupus can affect the body, for example in nearly all individuals that suffer from lup

Answer: It's a pretty good paper but in the beginning you made an error. There are four types of Lupus. Neo Natal (babies), Drug Induced, Discoid and Systemic. Then after that you should state that your paper is talking about Systemic Lupus because they symptoms you go on to describe are those of Systemic Lupus. Your citings follow the APA guidelines. I couldn't see the entire paper as it got cut off. Also couldn't see your works cited page. You don't show any quotation marks so I'm assuming that you didn't plagerize any of the information directly from the material.

Question: pls react on this journal... your reaction would be a great help...thanks God Bless? 'Multi-target' Immune Therapy Improves Outcomes Of Severe Lupus Nephritis ScienceDaily (July 7, 2008) — A new treatment using a combination of drugs targeting different parts of the immune system improves the recovery rate for patients with severe lupus involving the kidneys, according to a new report. "In our study, multi-target therapy is shown to be superior to traditional therapy for inducing complete remission of class V+IV lupus nephritis, with few side effects," comments Dr. Lei-Shi Li of the Research Institute of Nephrology of Jinling Hospital, Nanjing University School of Medicine in Nanjing,China. The study included 40 patients with severe lupus nephritis. Lupus nephritis is inflammation of the kidneys occurring in patients with the immune system disease systemic lupus erythematosus (SLE). All patients had "class V+IV" disease, meaning widespread inflammation and decreasing function of the kidneys. "This is a severe form of lupus nephritis that is traditionally treated with a single immunosuppressant drug, but the efficacy is very poor," says Dr. Li. "We considered that, since the impact of severe SLE on the kidney involves various parts of the immune system, it is necessary to treat the different immune targets with a combination of immunosuppressant drugs." One group of patients received this "multi-target" therapy, consisting of the immunosuppressant drugs tacrolimus and mycophenolate mofetil--commonly used as anti-rejection drugs in transplant patients--plus a steroid. The other group received standard treatment with a single immunosuppressant drug (cyclophosphamide). The complete remission rate, with recovery of normal kidney function, was about four times higher among patients receiving the three-drug combination. "For patients receiving multi-target therapy, the complete remission rate reached 65 percent at nine months, versus only 15 percent under traditional therapy," says Dr. Li. Some patients in both groups had partial remission, with some return of kidney function. Overall, 95 percent of patients in the multi-target therapy group had partial or complete remission, compared to 55 percent with single-drug therapy. The rate of most adverse effects was also lower with multi-target therapy. Systemic lupus erythematosus is an autoimmune disorder, in which the immune system attacks healthy organs and tissues. By reducing immune system activity, treatment with immunosuppressant drugs has improved most outcomes for patients with SLE. However, class V+IV lupus nephritis continues to be a major problem--it has a poor response to traditional treatments and can lead to permanent kidney damage. "The prognosis is very poor, so it is important for us to develop a new regimen for the treatment of this type of lupus nephritis," says Dr. Li. Using a combination of drugs that affect different immune targets, multi-target therapy improves the chances of remission for patients with severe lupus nephritis. "The therapeutic effect of our multi-target therapy is apparently superior to traditional therapy for inducing complete remission of Class V+IV lupus nephritis, and also bears good tolerance under relatively lower dosages," Dr. Li adds. The authors stress that their study is only preliminary. The study includes a small group of patients from a single hospital, with a relatively short follow-up time. Larger randomized trials with longer follow-up are required.

Answer: ok, a journal on lupus intersting if your an immunologist or for this type of lupus a nephrologist or just interested in lupus

Question: Can "drug-induced lupus erythematosus" be the reason behind the death of Michael Jackson? Since as it was known he had two severe illnesses "vitiligo" and "lupus".

Answer: The number one cause of death for people with systemic lupus erythematosus is cardiovascular events like heart attacks. Jackson had systemic lupus. He did not have drug induced lupus. With drug induced lupus, if the offending drug (high blood pressure medications, tuberculosis meds, etc) is withdrawn, the lupus goes away Lupus can be painful. The drugs that he took to control his pain, along with the lupus, could have caused his death.

Question: This is a lot to ask, I know. But if someone could review my APA paper I would GREATLY appreciate it. ? I think my greatest problem is with grammer errors and my in-text citations. Also, all of those citations that repeat themselves look funny to me. They can't be right? Can they? I'm also confused with secondary citations. I think they're a no no but I can't get a clear answer on what they are. Here's the paper. Please kindly review if you'd like. I'd love yah for it. Kisses Mandi (Title page & reference page not included) Introduction Lupus is an autoimmune disease that permits the affected body to build antibodies to attack its own cells as if they were foreign. There are three main types of lupus. They are discoid, drug induced, and Systemic lupus erythematosus (Encyclopedia Britannica, 2009). Doctors must be careful in diagnosing lupus since it can easily be confused with other diseases (Rahman & Isenberg, 2008). Lupus is capable of attacking any part of the body but for the most part it mainly affects the skin, kidneys, joints, heart, gastrointestinal tract, and serous membranes (Encyclopedia Britannica, 2009). The cause of Lupus is currently unknown. Lupus truly is a sickness of mystery since the cause and cure have currently been unidentified. However, there are known genetic (Encyclopedia Britannica, 2009) and environmental (Rahman & Isenberg, 2008) aspects that have been known to trigger this illness. On an inspiring note, there is presently a study being conducted with mice in search for the cure of lupus. Discussion Lupus is an autoimmune disease that is known to be a chronic (continuous or reoccurring) inflammatory illness that has the ability to attack any region of the body (Encyclopedia Britannica, 2009). The symptoms of the disease are painful or swollen joints and muscle pain, unexplained fever, red rashes, chest pain when breathing deeply, loss of hair, pale or purple fingers or toes from cold or stress (also known as Raynaud's phenomenon), sensitivity to the sun swelling in legs or around eyes, mouth ulcers, swollen glands and extreme fatigue (WebMD, 2008). Those that suffer from lupus may never have the same symptoms as another person with the disease (Encyclopedia Britannica, 2009). However, the most common areas of the body affected are the skin, kidneys, joints, heart, gastrointestinal tract, and serous membranes (Encyclopedia Britannica, 2009).. Also in most cases in order for a doctor to diagnose lupus the patient must illustrate at least four (Encyclopedia Britannica, 2009) of the listed symptoms. The actual cause of the disease is unknown. However, there are genetic and environmental characteristics that could trigger lupus to develop. Many patients that suffer from lupus have a genetic association with the disease (Encyclopedia Britannica, 2009). Lupus could be the result of mutated genes of interferon and the genes that play vital roles in regulating the immune response (Encyclopedia Britannica, 2009). If a patient has a genetic link to lupus there are also environmental aspects that could trigger lupus. They are infection, ultraviolet light, certain drugs like; procainamide, hydralazine, and quinidine (Rahman & Isenberg, 2008), and extreme stress (Encyclopedia Britannica, 2009). Factors that potentially contribute to the progression of lupus are interleukins and interferons (immune molecules). Interleukins and interferons have been shown to control the autoantibody release in response to certain bodily stimuli (Encyclopedia Britannica, 2009). Lupus commonly affects women, African Americans, and Asians more than any other group (Rahman & Isenberg, 2008). Since 90% of all patients with lupus are female, women between the ages of 15-50 should be tested for lupus if they portray at least one of the symptoms (Rahman & Isenberg, 2008). Also, there is an increased risk of lupus in people who already have the Epstein-Barr virus. (Rahman & Isenberg, 2008) The healthy immune system’s mission is to protect the body from infections and foreign objects within the body. When the immune system is working properly it will recognize the foreign bacteria, virus, or objects as non-self. Upon recognition that something does not belong, it will build antibodies against the unwanted agent, attack and destroy it (Marieb, 2009, p. 408 & 410). However, the activities of the immune system are much different when the body is affected with lupus. Instead of the body producing antibodies against foreign bacterial that do not belong, the immune system will produce an autoantibody that attacks the body’s own cells and tissues. The reason for this is because they can not recognize their own cells or tissue as self. When an autoantibody attack occurs, the autoantibodies will attach themselves to various tissues and cells (Rahman & Isenberg, 2008). When this happens the body’s inflammatory response occurs. The same thing happens when we have been hurt and the tissue has truly been damaged. There are a few different ways Lupus can affect the body, for example in nearly all individuals tha

Answer: Get rid of all the citations that are repeating themselves,that a big no no.Use each citation only once ok.I think alround its great and you should get a good grade.Hope it helps