Get the facts on Incontinentia Pigmenti treatment, diagnosis, staging, causes, types, symptoms. Information and current news about clinical trials and trial-related data, Incontinentia Pigmenti prevention, screening, research, statistics and other Incontinentia Pigmenti related topics. We answer all your qestions about Incontinentia Pigmenti.
Question: Can anyone tell me any statistics of Incontinentia Pigmenti in the Philippines?
Answer: try this website
http://www.medhelp.org/
Question: Can women with Incontinentia Pigmenti have children?
Answer: They are not infertile, but it is a genetic disorder, so some counselling might be in order before trying to conceive. It can be lethal in males and about half of female children will have the disorder.
Question: Is there anybody out there who has or knows of anyone with incontinentia pigmenti would like to discuss?
Answer: try google or ask.com
Question: anyone heard of Incontinentia Pigmenti - rare genetic condition?
Answer: From the National Institute of Neurological Disorders and Stroke Web site, (http://www.ninds.nih.gov/disorders/incon… Accessed September 6, 2006:
Incontinentia pigmenti (IP) is one of a group of gene-linked diseases known as neurocutaneous disorders. These disorders cause characteristic patterns of discolored skin and also involve the brain, eyes, nails, and hair. In most cases, IP is caused by mutations in a gene called NEMO (NF-kappaB essential modulator). Males are more severely affected than females. Discolored skin is caused by excessive deposits of melanin (normal skin pigment). Most newborns with IP will develop discolored skin within the first two weeks. The pigmentation involves the trunk and extremities, is slate-grey, blue or brown, and is distributed in irregular marbled or wavy lines. The discoloration fades with age. Neurological problems include cerebral atrophy, the formation of small cavities in the central white matter of the brain, and the loss of neurons in the cerebellar cortex. About 20% of children with IP will have slow motor development, muscle weakness in one or both sides of the body, mental retardation, and seizures. They are also likely to have visual problems, including crossed eyes, cataracts, and severe visual loss. Dental problems are also common, including missing or peg-shaped teeth
