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Amyloidosis Lichen

Get the facts on Amyloidosis Lichen treatment, diagnosis, staging, causes, types, symptoms. Information and current news about clinical trials and trial-related data, Amyloidosis Lichen prevention, screening, research, statistics and other Amyloidosis Lichen related topics. We answer all your qestions about Amyloidosis Lichen.

Question: Can Amyloidosis Lichen be cure ?

Answer: This is the most common form of primary localised cutaneous amyloidosis. It presents as an intensely itchy rash on the shins, thighs, feet, and forearms. Lesions consist of multiple raised spots (papules) that are scaly and red/brown in colour. Papules may coalesce into thickened plaques. It appears to be more common in people of Chinese descent and in males. It most often occurs between 50-60 years of age. It may be a variant of lichen simplex. Primary cutaneous amyloidosis is classified into three types: macular, lichen (papular), and nodular. Biphasic amyloidosis is a rare entity characterized by the presence of concurrent lesions of macular and lichen amyloidosis. The macular lesions tend to be distributed on the inter-scapular area and thighs while the papular lesions are most commonly present on the arms and lower legs. The occasional transformation of macular amyloidosis into lichen amyloidosis has been observed. The pathogenesis of cutaneous amyloidosis is poorly understood. There are reports in the literature in which macular amyloidosis developed secondary to chronic friction induced by nylon bath sponges, pumice stones, and coconut fibers. However, larger case series have failed to show a correlation between areas subjected to repeated friction and the development of cutaneous amyloidosis. As already mentioned, there is a higher incidence of cutaneous amyloidosis in Southeast Asia and South America, which implicates a possible genetic or environmental etiologic factor. Indeed, most previously reported cases of biphasic amyloidosis are from Asia. The treatment of lichen and macular amyloidosis is focused on relieving itch. Sedating antihistamines can be moderately effective. There is no cure for most cases of amyloidosis lichen. Some medications, such as corticosteroids, chemotherapy agents and colchicine, may decrease inflammation and treat some cases of amyloidosis lichen, but they are not very effective if the disease is severe or highly advanced. Peripheral blood stem cell transplantation involves using high-dose chemotherapy and transfusion of previously collected immature blood cells (stem cells) to replace diseased or damaged marrow. Attacks of fever, joint, and abdominal pains, can be prevented with the medication colchicine. Other treatments tried include topical dimethyl sulfoxide (DMSO) and phototherapy (UVB) or PUVA). I add a link containing details of this subject http://www.emedicine.com/ derm/topic16.htm Hope this helps Matador 89


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