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Undifferentiated Connective Tissue Disease

Get the facts on Undifferentiated Connective Tissue Disease treatment, diagnosis, staging, causes, types, symptoms. Information and current news about clinical trials and trial-related data, Undifferentiated Connective Tissue Disease prevention, screening, research, statistics and other Undifferentiated Connective Tissue Disease related topics. We answer all your qestions about Undifferentiated Connective Tissue Disease.

Question: What is Undifferentiated Connective Tissue Disease in lamens terms? I'm going with my girl friend to the doctor and I want to ask some questions about this disease but dont' know what to ask?

Answer: It means that they know it is a connective tissue disease, but don't know which one because it isn't fitting all the criteria at this point. You might want to ask what will happen next in the course of the disease, about complications, etc. Looking up the different CTDs might give you more of an idea what to ask. "Many connective-tissue diseases (CTDs) share common signs and symptoms, which frequently makes the diagnosis of a specific rheumatic disease difficult. Rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis (SSc), polymyositis (PM), dermatomyositis (DM), mixed connective-tissue disease (MCTD), and Sjögren syndrome (SS) can present with similar clinical features, particularly during the first 12 months of symptoms. Isolated Raynaud phenomenon, inflammatory polyarthritis, anemia, interstitial lung disease, or pleuropericarditis may occur without an obvious diagnosis. Screening serology findings, such as rheumatoid factor (RF) or antinuclear antibody (ANA), may be positive or negative under these clinical circumstances. However, well-established connective-tissue diseases have defined, discrete diagnostic criteria. Patients who present with symptoms, positive serology results, or physical findings consistent with an established connective-tissue disease but not fulfilling classification criteria for one of these established connective-tissue diseases are diagnosed with undifferentiated connective-tissue disease (UCTD). UCTD is a relatively new entity, suggested by LeRoy et al in 1980. The definition of UCTD is still under debate, although it is becoming more clear. Mosca et al recently reviewed UCTD literature and proposed that preliminary classification criteria include (1) signs and symptoms suggestive of a connective-tissue disease, (2) positive ANA results, and (3) a disease that lasts at least 3 years."

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