Wilson Disease

Question: What does Wilson's disease have to do with the thyroid? My sister may be having problems with her thyroid, the doctor is testing her for Wilson's disease, what does this disease have to do with that? I understand what Wilson's disease is, please don't post descriptions of it. I'm wanting to know what the thyroid has to do with the disease.

Answer: Excessive copper can get deposited anywhere and thyroid gland, though very uncommonly affected, may therefore get affected. Therefore the necessity of thyroid tests for ruling out any consequences. However, you may like to confirm the diagnosis of Wilson’s Disease yourself, which is quite easy. Look for a 2-3 mm brownish circular ring on cornea about 1-3 mm from the periphery of the cornea in both the eyes of your sister. The presence of this ring is a definite sign for Wilson’s disease and thereafter you may continue to trust and follow whatever advice he/she may provide. In early diagnosis, this ring may be incompletely formed and may not encircle the whole cornea.

Question: Does the medical exam during MEPS test for Wilson's Disease? Just like I'm asking. I've been reading about Wilson's Disease a lot recently for a project, and, of course, I've a friend that has some of the symptoms. She's just under 21. I'm not a doctor, nor am I planning on being one. I'm just kinda curious, I suppose. Anyway, she went through the physical exam during MEPS (she's joining the USAF), and I'm wondering if they would've easily caught Wilson's Disease or not.

Answer: To find Wilson,s without obvious signs such as brown around the iris (actually copper) you would probably have to have blood work drawn for heavy metals, family history, and other signs and sx's. To catch it depends on the dr.

Question: Do people suffering from wilson's disease in Canada drink tap water? In canada, the water pipes are made of copper. is it recommended for them to drink tap water?

Answer: You are obviously aware of the symptoms and cause of Wilson’s disease. Suffice it for me to mention that the disease is diagnosed through tests that measure the amount of copper in the blood, urine, and liver. An eye exam would detect the Kayser-Fleischer ring. The disease is treated with lifelong use of D-penicillamine or trientine hydrochloride, drugs that help remove copper from tissue, or zinc acetate, which stops the intestines from absorbing copper and promotes copper excretion. Patients will also need to take vitamin B6 and follow a low-copper diet, which means avoiding mushrooms, nuts, chocolate, dried fruit, liver, and shellfish. Wilson disease requires lifelong treatment. If the disorder is detected early and treated correctly, a person with Wilson disease can enjoy completely normal health. If you require more detailed medical information, you would be advised to consult your doctor, or contact the link which I add below – Wilson's Disease Association 4 Navaho Drive Brookfield, CT 06804 Phone: 1–800–399–0266 or 203–775–9666 Email: hasellner@worldnet.att.net Internet: www.wilsonsdisease.org Hope this helps matador 89

Question: What metal caused Wilson and Minamata disease? What are the signs and symptoms?

Answer: wilsons: copper minamata: mercury

Question: What type of karyotype does Wilson's Disease have? karyotype for wilson disease

Answer: It's on chromosome 13 (13q14.3)...here are some links.

Question: What type of genetic disorder is the Wilson's disease? Please be specific with answer, thank you^.^

Answer: Wilson's disease is a copper overload syndrome caused by a defect in the amount of production of ceruloplasmin, a protein that binds and helps eliminate copper. The high blood levels of copper infiltrate and deposit in all organs of the body, e.g. the brain, the eyes, the heart, the liver, the kidney, etc... Wilson's disease can be managed by eating a low copper diet, and taking chelating agents (agents that bind copper and eliminate it). Hope it helps some.

Question: Where could I find a picture of the karyotype for Wilson Disease? pic of karyotype

Answer: Wilson's Disease is due to a mutation in the gene that helps bind and eliminate copper from the body (ceruloplasmin?). It is not a chromosomal disorder, but rather due to only a specific mutation of one specific gene. Therefore a karyotype would appear normal visually since its not due to any gross chromosomal abnormality like translocations or deletions. Here, I found a site that explains its inheritance http://www.wilsonsdisease.org/content_su…

Question: could someone tell me if thyroid trouble is linked to wilson's disease? i was diagnosed with hypothyrodism, as a baby, and have been disgnosed with wilson's disease since i was 18 years old im 37 years old now

Answer: Yes it is a thyroid problem.Check out the yahoo group by Mary Shomon. thyroid is the name.Also you should check out the book by David Brownstein M.D. Overcoming Thyroid Disorders.

Question: Type of mutation involved in Wilson's disease? What type of mutation causes Wilson's disease. the word i am looking for is deletion, inversion, translocation, nondisjunction, point mutation, or frameshift mutation

Answer: A point mutation - substitution.

Question: what is Wilson disease? about wilson disease

Answer: Wilson’s disease is a rare genetic disorder characterized by excess copper stored in various body tissues, particularly the liver, brain, and corneas of the eyes. The disease is progressive and, if left untreated, it may cause liver (hepatic) disease, central nervous system dysfunction, and death. Early diagnosis and treatment may prevent serious long-term disability and life threatening complications. Treatment is aimed at reducing the amount of copper that has accumulated in the body and maintaining normal copper levels thereafter.