Supranuclear Palsy

Question: Can anyone help with information on proper diagnosis and treatment for Progressive Supranuclear palsy? mother recently diagnosed w/PSP - i have reason to suspect a hasty misdiagnosis and would like the best possible recommendations for proper course to follow.

Answer: The diagnosis of PSP is based on the physical examination (the eye movement problems are quite characteristic, but are not always present early in the disease course) and on ruling out other, similar movement disorders such as Parkinson's disease, Creuzfeld-Jacob disease etc. If I had any concerns about the diagnosis of one of my relatives, I would definitely seek second opinion from a trusted neurologist who is specializing in movement disorders. There is currently no effective treatment for PSP. Antiparkinsonian medications and antidepressant medications have been tried, with a little improvement in some patients. Supportive therapies can include walking aids, physical therapy, feeding tube placement. There are some research trials going on, you can check the National Institutes of Health website (clinicaltrials.gov) for the latest. Good luck to you and your mom. I added some links below.

Question: Is progressive supranuclear palsy (PSP) a demyelinating disease? I know the symptoms and the conditions of people with the disease, but I don't know if the degeneration has to do with the myelin of the nerves or if it is from some other factor.

Answer: i cant be sure... its related to parkinsons and alzheimers so i think it might be but the damage is so specific that i think damage to the myelin would cause more widespread damage... but dont take my word for it.

Question: Does anyone in this world know of any case of Progressive Supranuclear Palsy getting cured/ better? Progressive Supranuclear Palsy (PSP) info www.psp.org Has any of the traditional or alternate therapy proved worthwile in PSP patients?

Answer: Homeopathic Remedies prescribed according to the patients symptoms not of the disease will help treat and cure it. Homeopathy will not treat Progressive Supranuclear Palsy (PSP) it will treat and cure the person who is affected by it by treating the patients symptoms. The symptoms of the patient and details about him not the name of the disease. Please post your details exactly the way you feel them from head to toes. Take Care and God Bless you !

Question: A disease similar to progressive supranuclear palsy? My grandfather died three years from a disease that was similar to progressive supranuclear palsy. He was a construction worker for close to 50 years and retired finally when we was about 69. (sorry for adding that I just have a very intense feeling of pride for him) His symptoms started about a year after his retirement and was first diagnosed as Alzheimer's. Then about a year after that they told us it was PSP, finally about a year before he died the neurologist told us it was a different disease because it only affected the one side of his body I believe was the reasoning behind the new diagnosis. The doctor told us that although it was similar to PSP it was a totally different disease none the less. I believe it also had to do with his nerves dying as well as parts of his brain. By the end he could barely move at all and was bedridden, his vocal skills were gone although he still was totally aware of his surrounding and the people he loved and knew, thank you for your time. ran out Thank you for you time my grandmother woke up finally and told me it was cortical basal ganglionic degeneration, if anyone knows of a site that explains what it is in plain terms please let me know so far everything I have found are basically medical journals. Thanks again for your time. Thank you for you time my grandmother woke up finally and told me it was cortical basal ganglionic degeneration, if anyone knows of a site that explains what it is in plain terms please let me know so far everything I have found are basically medical journals. Thanks again for your time.

Answer: have you tried sites like mayo clinic or searching medical journals? google does good journal searches you might have better luck searching your Grandfathers symptoms that way especially since you cannot fully fit it in here. I wish I had more information for you. If you have 'health team' at your doctors office they some times have a phone nurse you could call them and ask though I am not sure how much neurology background your average family practice nurse might have. Best of luck finding answers.

Question: Who is the best homeopathy Dr. in India treating patients with hypothyroidism AND PSP(Para Supranuclear Palsy) My Father is suffering from hypothyroidism and Para Supranuclear Palsy.Who is the best homeopathic Dr. in Delhi NCR or India whom we can contact.The disease has no cure in Ayurvedic and Allopathy. Thanks-Rajiv Chandna

Answer: Contact Delhihomeo.com for referral to the Homeopathic doctor who can treat your father's condition. Good luck!

Question: Treatment for PROGRESSIVE SUPRANUCLEAR PALSY ( PSP)? I am from Kerala in India. My beloved father aged 81 years was diagnosed to be having PROGRESSIVE SUPRANUCLEAR PALSY (PSP) about one and half years back.This is a Parkinson Plus movement disorder in Pakinsonism (variant of Parkinson disease) group of diseases.His body balance is lost and cannot stand on his foot,his speech is not legible,he has swallowing difficulty which might result in choking or aspiration of food into lungs, his eye ball movement is restrained etc. etc....Allopathy says this is due to progressive degeneration of brain cells (nuerons) controlling movements in the body and there is practically no treatment for this disease. They have been giving him Syndopa Plus(100+25) 11/2 Tabs 3 times daily. Is there any treatment in any system of medicine? Please help!This is an appeal from a son to save his very very affectionate father.

Answer: Sorry to hear your dad is ill, I guess this isn't really what you want to hear but this is what I came up with. There is currently no effective treatment for PSP, although scientists are searching for better ways to manage the disease. In some patients the slowness, stiffness, and balance problems of PSP may respond to antiparkinsonian agents such as levodopa, or levodopa combined with anticholinergic agents, but the effect is usually temporary. The speech, vision, and swallowing difficulties usually do not respond to any drug treatment.. Another group of drugs that has been of some modest success in PSP are antidepressant medications. The most commonly used of these drugs are Prozac, Elavil, and Tofranil. The anti-PSP benefit of these drugs seems not to be related to their ability to relieve depression. Non-drug treatment for PSP can take many forms. Patients frequently use weighted walking aids because of their tendency to fall backward. Bifocals or special glasses called prisms are sometimes prescribed for PSP patients to remedy the difficulty of looking down. Formal physical therapy is of no proven benefit in PSP, but certain exercises can be done to keep the joints limber. A surgical procedure, a gastrostomy, may be necessary when there are swallowing disturbances. This surgery involves the placement of a tube through the skin of the abdomen into the stomach (intestine) for feeding purposes. Good wishes to you and your family

Question: what goes wrong in progressive supranuclear palsy?

Answer: The ultimate cause appears to be unknown, but there is degeneration of the "supranuclear" - pea-sized brain structures that control eye movement. See references, below.

Question: Anyone had a patient with Progressive Supranuclear Palsy? If so what guided your DDX?

Answer: at this level of suspiscion you should be in contact with a neurologist to ensure correct diagnosis, good luck

Question: Progressive Supranuclear Palsy? Does anyone know how this disease is transmitted/concieved? Is it genetic, or does someone have to be exposed to a substance of some sort (chemicals/radiation/etc)? Can it be passed down to family members?

Answer: PSP is a rare degenerative neurological disorder. The cause is unknown. It is unknown whether PSP is caused by hereditary factors, environmental factors, or a combination of both.. It is not "transmitted or conceived"...it just happens. It is often misdiagnosed as Parkinson's disease.

Question: Enzymes and Degenerating cells question.? I’m working on a short story, and I need input on some of the science. Would it be plausible to have an enzyme from an as yet undiscovered fungus that can promote either healing among degenerating cells or regeneration of dying cells? And promote it significantly enough to use as a possible treatment for diseases like Progressive supranuclear palsy, Amyotrophic Lateral Sclerosis, and multiple system atrophy. If this isn’t plausible, could you suggest a way to tweak it and make it more plausible? Thanks!

Answer: The only thing not plausible might be the method of delivery. Enzymes are proteins, and as such, are susceptible to degradation by proteases, and the like. So, you might want to find a way of protecting the enzyme while delivering it to the subject. Good luck with your story.

Question: Is anyone aware of any case of Progressive Supranuclear Palsy or a condition similar to it being cured? Does anyone personally know any patient of PSP being cured? I need to contact that ex-PSP patient urgently.

Answer: FINDING PSP PEOPLE The Society for Progressive Supranuclear Palsy -- http://www.psp.org/ -- has a Forum, where people with PSP talk. The Society may be able to help you find someone local or electronic to communicate with. TREATMENT Treatment news is not good. This eMedicine article -- http://www.emedicine.com/neuro/topic328.… -- covers current state of the art. Clinical trials for PSP -- some therapeutic, some diagnostic -- are under way in the USA. * http://www.clinicaltrials.gov/ct/show/NC… ( Effects of Coenzyme Q10....) * http://www.clinicaltrials.gov/ct/show/NC… (Valproic Acid not yet recuiting) * http://www.clinicaltrials.gov/ct/show/NC… (Risk Factors) * http://www.clinicaltrials.gov/ct/show/NC… (Distractibility Syndrome ...) * http://www.psp.org/research_center.asp (genetic and environmental risk factors) Good luck.

Question: what goes wrong in progressive supranuclear palsy?

Answer: Your question is not comprehensible as currently written. Please revise your question and add details for assistance. I will check back and assist you further at that time.

Question: what illness is psp? what illness is progressive supranuclear palsy

Answer: Progressive supranuclear palsy (PSP) is a rare degenerative disease of the brain. The disease impairs movements and balance. Many people with PSP also experience changes in mood, behavior, and personality. A decline in cognitive mental processes, such as thinking, memory, attention, and speech, is not uncommon. When these mental changes are severe enough to interfere with everyday activities, they are called dementia. See link for more:

Question: Myasthenia Gravis? My grandfather is in the ICU right now and I'm trying to understand this disease. He was having a ten day treatment with a shunt in his chest cavity to filter protein from his blood however the shunt going into his chest caused his heart rate to drop to 30, so the doctor stopped and said he couldn't continue. They are now doing an IV treatment (which I am researching because they did not tell my grandmother what it does and how it does it and what risks are involved.) for 5 days. He cannot eat or swallow anything and he just falls down for no apparant reason. Does anyone know about this disease? I don't think he has this problem, his symptoms don't point to it really. I suppose it could be this disease in combination with another that I believe he has (I think he has Progressive Supranuclear Palsy) but when I told my grandmother to ask them to run tests they said no. Can she make them check him for that? I am really reading everything I can get my hands on and all signs point to PSP.

Answer: Myasthenia gravis is an autoimmune disorder, that causes muscle weakness and excessive muscle fatigue. It is not inherited, and is more common in men over 50 yet more common n females below that age. Symptoms of generalized form and occular form lists of tests, treatments and other disorders that present the same can be found at www.muscular-dystrophy.org it is an exellent site. If you are not satisfied with the doctors diagnosis seek second and third opinions. Is it a neurologist hes seeing? There is a blood test for myasthenia gravis, has he had it? I would also suggest if you can go to the hospital and ask the doctors to explain it to you. There are many disorders that can present in the same manner, there is probably a very good reason they have diagnosed it as this. I hope the website helps with your search. Best of luck!! And my best wishes for your Grandfather.