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MELAS

Get the facts on MELAS treatment, diagnosis, staging, causes, types, symptoms. Information and current news about clinical trials and trial-related data, MELAS prevention, screening, research, statistics and other MELAS related topics. We answer all your qestions about MELAS.

Question: I know of someone who has a rare disease called "MELAS SYNDROME" is there any known doctor or treatment MELAS syndrome is a rare form of dementia. MELAS is an abbreviation of episodes.

Answer: There is no known treatment for the underlying disease, which is progressive and fatal. Patients are managed according to what areas of the body are affected at a particular time. Enzymes, amino acids, antioxidants and vitamins have been used, but there have been no consistent successes reported. Although there have been no controlled trials on long-term benefits of dietary manipulations. The following supplements have shown promise, and given hope to MELAS patients. CoQ10 has been helpful for some MELAS patients. Nicotinamide has been used because complex l accepts electrons from NADH and ultimately transfers electrons to CoQ10. Riboflavin has been reported to improve the function of a patient with complex l deficiency and the 3250T-C mutation. The administration of L-arginine during the acute and interictal periods may represent a potential new therapy for this syndrome to reduce brain damage due to impaired vasodilation in intracerebral arteries owing to nitric oxide depletion


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