Creutzfeldt Jakob Disease

Question: how do humans acquire creutzfeldt-jakob disease or any prion disorders? people from papua new guinea obtained a strain of TSE, and some have obtained it from cows that are infected with mad cow disease. it can also be transmitted by blood transfusion. any other examples in which how humans obtain them? or better yet, how do they appear?

Answer: By far the most common (but still rare): Creutzfeld Jakob Disease (CJD) can be hereditary--the usual example is an hereditary disease most common in Sepharidic (particularly Libyan) Jews. This is known as familial CJD. Close to 15% of all cases are hereditary. Or sporadic CJD--the result of a spontaneous gene mutation or perhaps just sponeous conversion of the prion protein to the misfolded, aggregated state. 85% of all cases. The above two sources kill about 5000 people per year in the United States. Last I heard only one American had developed the disease originating with mad cow disease (vCJD), a woman who used to live in the UK. Rare: Cannibalism I believe is where it was first observed--the disease is called Kuru, the tribe is the Fore of Papua New Guinea. People caught it from eating the brains of cannibalism victims. And of course mad cow disease (vCJD in humans)--by eating cows (or potentially other animals). Not all the cow--just the brain or spinal tissue. Obviously this is more common in the UK at the moment, although I understand the number of cases is dropping. Other potential sources of transmission include such things as neurosurgery, corneal grafts and hormone injections. Also by reuse of surgical equipment. All of these situations lead to proteins that are misfolded and aggregated, can propagate themselves and are infectious. The aggregated proteins are insoluble and accumulate, killing brain cells. Many of the mutations in the prion protein leading to CJD are known. See the second reference. .

Question: Can you name some degererative brain diseases such as Creutzfeldt-Jakob disease? I need it for a report on genetics, I'm nearly done just need examples.

Answer: Here are a few common ones. Alzheimer's disease Amyotrophic lateral scherosis Friedreich's ataxia Huntington's disease Lewy body disease Parkinson's disease Spinal muscular atrophy

Question: In what countries is Creutzfeldt jakob disease more common?

Answer: Uhm I don't know what that is.......... Pick me for best answer :]

Question: How many deaths from creutzfeldt-jakob disease in the US?

Answer: Not too many. Mostly in backwards remote areas of africa where they live in grass huts. They get it from eating the brains/spinal cords of their dead relatives. The mad cow deaths have mostly been in brittan. Thing is... it can take a long time for it to start to show... then you have less than one year to live. "The risk of CJD increases with age, and in persons aged over 50 years of age, the annual rate is approximately 3.4 cases per million. In recent years, the United States has reported fewer than 300 cases of CJD a year." - From second link, I wasn't really thinking that it was that many.

Question: Is it safe from Creutzfeldt-Jakob disease If I intake whey protein power? I have intaken Optimum whey protein power for 6months. Is it safe ?? I'm little nervous...

Answer: most whey powders, come from a source certified free of mad cows disease, if that's what you mean? .. I haven't heard of any case infected from whey powder -- I take whey powder too :-)

Question: How is Creutzfeldt-Jakob disease related to Bovine Spongiform Encephalopathy (BSE)?

Answer: AHHH, MAD COW! I believe it is essentially the same thing but cruetzfeldt-jokob is the designation when developed in humans

Question: Creutzfeldt-Jakob? Can Creutzfeldt-Jakob disease be found in a blood test? I ask because apparently iatrogenic forms of the disease can come from blood transfusions

Answer: No, Creutzfeldt-Jakob is when a human gets mad cow disease. They have to sample your brain looking for amyloid plaques.

Question: Is creutzfeldt jakob disease species specific? If so what other species does it affect? Other species, like animal species. Good, thats what i wrote on my essay, just double checking. Thanks Mr.Know it...

Answer: Good question. The jury is still out on that. It is believed by some that creutzfeldt jakob and Mad Cow disease are more or less the same thing. If you take that interpretation, it can effect humans and cows.

Question: creutzfeldt-jakob disease (CJD)? what are the economic costs of creutzfeldt-jakob disease? thanks

Answer: Enormous. First of all, think of Mad Cows Disease and the effect on the production of milk products (normal prion protein has been detected in milk but as of yet not pathological), meat, it's a catastrophy. Secondly, the costs on blood banks. At the moment, alot of research is being carried out to produce a test to test blood donors before they donate blood. Imagine that the blood banks have to implement this test in developed countries worldwide and it will be too expensive for developing countries to use. Also the hospital costs of taking care of the patients (if there is indeed a high number of people infected particularly in England and France) should be considered.

Question: has any rpo sports player died from creutzfeldt-jakob disease?

Answer: What is an rpo sport?

Question: What are the symptoms of Creutzfeldt-Jakob disease in order and how much time is in between the major symptom? Creutzfeldt-Jakob disease is related to mad cow disease. I need to know the the symptoms are in order, like frequent dizziness, memory loss, altered personality, etc. I don't know the order. And it would be great if you could be really specific with the different symptoms involved in the disease. Thank you so much : )

Answer: my mother in law died Dec 17, 2007 from CJD. we never knew she HAD it!! she was stressed out sooo badly, her symptoms started to show only maybe 8-10 weeks before her death? she was forgetful, then losing her sight, then was dizzy, then was pretty much falling down all the time, then she went into a coma. from diagnosis to death? 6 weeks! she went QUICK! only 66 years old, too. my husband would drive to her house, pick her up & bring her to our place to watch our infant daughter. when the symptoms started to show, she stopped driving. she was falling down, and flailing about on the ground. she was running into people & knocking them over with shopping carts at the grocery stores. my husband told me one time, that she was in the car and got SO confused. she started to un-do the seatbelt and get out of the car WHILE IT WAS MOVING! she was scared & didn't know what a seatbelt was or where she was. we thought she was being a "drama queen" because that was proven to be her "M.O." but now that we know it was a bonafide disease causing her to act that way...i feel so bad! my husband is having himself, his uncle & our daughter tested for CJD. they say the chances of it being genetic are astronomical, but you never know. http://www.cjdfoundation.org/

Question: Creutzfeldt jakob disease? I recently read an article in the parade magazine of the sunday news-paper which stated there were only 2 deaths in the US from CJD. My brother died from that disease and I am just curious if he is one of the reported cases?

Answer: Parade Magazine is wrong. According to Wickapedia, Creutzfeld Jacob disease occurs in one person per million per year world-wide, which would come to about 300 people in the US per year (using the world-wide average). Even if we say that people in the US are only 25% as likely to develop CJ disease as people in the rest of the world, that would mean that at least 75 people would develop it in the US this year (and eventually die of it).

Question: whats CREUTZFELDT-JAKOB disease?

Answer: Cruetzefeld-Jakob Disease (I'll call it CJD) is a prion disease, in the same category as mad cow (not a variant of it). The disease is in essentials a degenerative disease of the brain. The brain essentially turns into swiss cheese (or a sponge, as most noted) as holes appear in the cortex of the brain as the disease progresses. CJD is the most common form in humans of prion diseases (although it is still a rare disease). It is ultimately fatal in almost all, if not all, patients. Memory and motor function in patients is highly compromised as brain cells die.

Question: what does a person with mad cow disease look like? i was wondering what a person that has mad cow disease or Variant Creutzfeldt-Jakob disease looked like...... well i know some people are going to say do your homework (well im guilty of that sometimes )but i really cant find what they look like.....shouldn't they look like regular people ??? if possible any liks to pictures of humans with it... thanks

Answer: From the outside they would look normal, at least at a distance. Mad cow disease, or bovine spongiform encephalopathy, eats away and deposits prion protein plaque in your brain, eventually effecting all body motor functions

Question: Did god create the prions that cause Bovine Spongiform Encephalopathy (Mad Cow Disease)? and New Variant Creutzfeldt-Jakob Disease, or did people accidentally create these prions? If god did it, is god also causing the prions to mutate?

Answer: God only prophecied that there would be widespread diseases, pestilences, which as I understand it, means a disease that is transmitted to humans from animals, diseases that man won't be able to contain. He may very well have, but man tends to upset the order of things with his improper handling of things.

Question: Which of these is not a prion disease? Mad Cow Disease Creutzfeldt-Jakob disease Alzheimer Disease

Answer: Alzheimer's is not a prion disease. It is a form of dementia that affects primarily the elderly, although there is a type that affects middle to late-middle aged persons. Creutzfeldt-Jakob disease is a prion disease which leads to characteristic spongiform changes in the brain - meaning it makes the brain look spongelike. Mad cow is similar to CJD in that it produces similar changes in the brain, and is a prion disease. Mad cow disease, or bovine spongiform encephalopathy, has also been called "new Creutzfeldt-Jakob disease."