Proteinuria

Question: proteinuria? Your doctor calls with the results of your urinalysis and tells you that they found proteinuria, the presence of abnormal amounts of protein in your urine sample. What could have caused this? a. Abnormal active transport of protein in Bowman’s capsule. b. Abnormal active transport of protein in the loop of Henle. c. Abnormally high concentration of plasma proteins. d. Glomerulonephritis (inflammation of glomeruli) due to localized damage there.

Answer: Ans.D Since serum proteins are readily reabsorbed from urine, the presence of excess protein indicates either an insufficiency of absorption or impaired filtration. Nephritis has the effect of damaging and closing up the microscopic filters in the kidney. This means that in addition to various toxic waste products, the inflamed kidney filters out important proteins (larger molecules) from the blood. Therefore the characteristic symptom of nephritis is proteinuria — meaning the excessive removal of protein from the blood and its excretion in urine.glomerulonephritis is inflammation is of the glomeruli ,the basic filtration unit of the kidney. (Often when the term "nephritis" is used without qualification, this is the condition meant.

Question: What happens when you have proteinuria and Type One diabetes? Two years ago, before I was diagnosed with type one, I was diagnosed with proteinuria. Last December, I was diagnosed with Type one diabetes. I haven't seen my kidney specialist since. But should I make an appointment? Is it possible that things are different now that I have diabetes? Thanks!

Answer: Yes , different and not for the better. Git with it , dialysis is a real pain. In fact , my cousin had two treatments and he ordered them to pull the plug. They did. And that is the rest of the story>>> What should a person do? If a person has diabetes, hypertension, or both, the first goal of treatment will be to control blood glucose, also called blood sugar, and blood pressure. People with diabetes should test their blood glucose often, follow a healthy eating plan, take prescribed medicines, and get the amount of exercise recommended by their doctor. A person with diabetes and high blood pressure may need a medicine from a class of drugs called angiotensin-converting enzyme (ACE) inhibitors or a similar class called angiotensin receptor blockers (ARBs). These drugs have been found to protect kidney function even more than other drugs that provide the same level of blood pressure control. Many patients with proteinuria but without hypertension may also benefit from ACE inhibitors or ARBs. The American Diabetes Association and the American College of Cardiology recommend that people with diabetes keep their blood pressure below 130/80.3 People who have high blood pressure and proteinuria, but not diabetes, also benefit from taking an ACE inhibitor or ARB. The Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure recommends that people with kidney disease keep their blood pressure below 130/80.4 To maintain this target, a person may need to take a combination of two or more blood pressure medicines. A doctor may also prescribe a diuretic in addition to an ACE inhibitor or ARB. Diuretics are also called “water pills� because they help a person urinate and get rid of excess fluid in the body. In addition to blood glucose and blood pressure control, the National Kidney Foundation recommends restricting dietary salt and protein. A doctor may refer a patient to a dietitian to help develop and follow a healthy eating plan. Tin

Question: What would cause my son to have proteinuria? How is this treated? Basically I am going out of my mind, as any mother would. I am worried about kidney damage. My son is only 5 years old. We have gone to the Dr to give urine samples twice this week, and on both days I was told his proteinuria was a 30, with 15 being the normal. He also has hematuria, I don't know how bad, but his Dr seems more concerned about the protein level. I would like to hear anyone's experience on this, and especially how it was treated. Thank you.

Answer: People with diabetes, hypertension, or certain family backgrounds are at risk for proteinuria. In the United States, diabetes is the leading cause of end-stage renal disease (ESRD), the result of chronic kidney disease. In both type 1 and type 2 diabetes, the first sign of deteriorating kidney function is the presence of small amounts of albumin in the urine, a condition called microalbuminuria. As kidney function declines, the amount of albumin in the urine increases, and microalbuminuria becomes full-fledged proteinuria. High blood pressure is the second leading cause of ESRD. Proteinuria in a person with high blood pressure is an indicator of declining kidney function. If the hypertension is not controlled, the person can progress to full renal failure. African Americans are more likely than Caucasians to have high blood pressure and to develop kidney problems from it, even when their blood pressure is only mildly elevated. In fact, African Americans are six times more likely than Caucasians to develop hypertension-related kidney failure. Other groups at risk for proteinuria are American Indians, Hispanic/Latinos, Pacific Islander Americans, older people, and overweight people. These at-risk groups and people who have a family history of kidney disease should have their urine tested regularly. What causes proteinuria? Protein should not normally appear in the urine in detectable quantities. It is usually kept in the blood by the filtering units (glomeruli) within the kidney. Proteinuria is an indicator that the kidneys are damaged in some way. Diseases that affect the filtering units themselves are the most common cause of heavy proteinuria. Sometimes this is called glomerulonephritis, meaning inflammation of the glomeruli. Just as some examples, any of the causes of nephrotic syndrome could be causes of proteinuria. How is proteinuria treated? If you have diabetes, hypertension, or both, the first goal of treatment will be to control your blood glucose and blood pressure. If you have diabetes, you should test your blood glucose often, follow a healthy eating plan, take your medicines, and get plenty of exercise. If you have diabetes and high blood pressure, your doctor may prescribe a medicine from a class of drugs called ACE (angiotensin-converting enzyme) inhibitors or a similar class called ARBs (angiotensin receptor blockers). These drugs have been found to protect kidney function even more than other drugs that provide the same level of blood pressure control. The American Diabetes Association recommends that people with diabetes keep their blood pressure below 130/80. People who have high blood pressure and proteinuria but not diabetes also benefit from taking an ACE inhibitor or ARB. Their blood pressure should be maintained below 130/80. To maintain this target, you may need to take a combination of two or more blood pressure medicines. Your doctor may also prescribe a diuretic in addition to your ACE inhibitor or ARB. Diuretics are also called "water pills" because they help you urinate and get rid of excess fluid in your body. In addition to blood glucose and blood pressure control, the National Kidney Foundation recommends restricting dietary salt and protein. Your doctor may refer you to a dietitian to help you develop and follow a healthy eating plan. For More Information American Kidney Fund 6110 Executive Boulevard Suite 1010 Rockville, MD 20852 Phone: 1–800–638–8299 or 301–881–3052 Email: helpline@kidneyfund.org Internet: www.kidneyfund.org National Kidney Foundation 30 East 33rd Street New York, NY 10016 Phone: 1–800–622–9010 or 212–889–2210 Email: info@kidney.org Internet: www.kidney.org

Question: How can glomerulonephritis cause both proteinuria/hematuria and uremia? If glomerular damage has increased the size of the filtering pores enough that large proteins or RBCs can pass through, why couldn't water do the same? Conversely, if glomerulerosis has decreased the size or number of those same pores enough to prevent or hinder the passage of H2O how could proteins/RBCs fit through? I'm obviously having some trouble with this concept and would appreciate any help. Thanks

Answer: The glomeruli of the kidneys are the parts that normally filter the blood. They consist of capillaries that are fenestrated (leaky, due to little holes called fenestrae or windows) and that allow fluid, salts, and other small solutes to flow through, but normally not proteins. In nephrotic syndrome, the glomeruli become damaged due to inflammation and hyalinisation (membrane formation) so that small proteins, such as albumins, immunoglobulins and anti-thrombin can pass through the kidneys into urine. Albumin is the major protein in the blood which maintains colloid osmotic pressure- this prevents leakage of blood from vessels into tissue. However, experiments show that the edema formation in nephrotic syndrome is more so due to microvascular damage and intense salt and water retention by the damaged kidneys (due to increased angiotensin secretion). The mechanism is very complex and still not fully understood. Uremia is the build up of urea, the metabolic by-product of protein metabolism. If the glomerulus is incompetent, then you basically end up poisoning your cells with urea. Water is lost in glomerulonephritis, but not through the kidneys, it ends up being third-space shifted into tissues due to the loss of the osmotic pressure from the protein plasma leakage. It manifests as ascites, pulmonary edema and generalised edema, (especially of the extremities). I hope this helps you understand where the water goes.

Question: Are the Proteinuria and E Coli in my dog related? If the EColi goes away with the antibiotics she's on, will the proteinuria go away, too? I'm worried about her.

Answer: You need to clarify this with your vet. The e-coli will be taken care of with the antibiotics, BUT proteinuria may be a sign of renal failure. Your vet will want to recheck the urine when the antibiotics are finished. If the proteinuria is still present after the infection is gone, further testing will need to be done to determine the reason for the protein in the urine.

Question: Medical professionals: Possible explanations for adolescent with proteinuria? 15 y.o. male had high amount of protein in urine as shown by dipstick today. His MD will repeat the dipstick next week & he'll have a fasting CBC. He has no major health history except mental health & has been on lithium for approx. 2 years. Lithium levels have been regularly monitored. His MD visit today was prompted by his drinking huge quantities of water--easily over 2 gallons a day--for the last few months. Dipstick glucose was normal. Can anyone offer ideas for the proteinuria?

Answer: There are many possiblities. Could be from the Lithium. Other possible causes for benign proteinurea: Dehydration Emotional stress Fever Heat injury Inflammatory process Intense activity Most acute illnesses Orthostatic (postural) disorder Try doing an internet search for proteinurea/albuminurea.

Question: Does diabnoses of Proteinuria require hospitalization? What if you also have Diabetes?

Answer: A diagnosis of proteinuria doesn't require hospitalization, but is a very serious condition that could be signalling impending kidney failure. Protein is normally broken down and filtered from the body by the kidneys and if protein is being found in the urine there is a good chance that your kidney function is abnormal. You probably didn't know that diabetes is one of the leading causes of kidney failure. If I were you I would get my creatinine tested immediately.This test will determine whether or not the kidneys are working correctly and give an accurate idea of the percentage of kidney function. If you are prone to procrastination remember this: kidneys do not repair themselves, and once they fail you will require dialysis or a kidney transplant in order to survive. Dialysis is a blood purification treatment that replaces the function of your kidneys and must be done 3 or 4 times a week for 3 or 4 hours at a time. I know all of this because i'm diabetic and my kidneys failed two months ago.

Question: Can excessive masturbation cause proteinuria? Can excessive masturbation cause proteinuria?

Answer: I would say it doesn't at all

Question: Why would a teenager have Proteinuria? check up shows this! Is this REALLY dangerous?

Answer: Proteinuria is when protein is in the urine. As blood moves through the kidneys, the kidneys filter out waste, excess fluid and salt. These wastes leave the body in urine. Usually, no protein is found in urine because most proteins are too big to go through the kidneys. Proteinuria is a sign that the kidneys are not working right. Sometimes infection or chemicals damage the kidneys, and this makes protein show up in the urine. If there's only a little protin in urine, you migt be suffering from orthostatic proteinuria. Orthostatic proteinuria occurs in some older children and teenagers. The word orthostatic means "upright." The condition is called "orthostatic proteinuria" because protein goes into the urine only when the child is standing up. Children with this condition have no kidney damage but, for some unknown reason, they lose protein into the urine during the day when they are active. At night, while they sleep, their kidneys don't let any protein into the urine. If this is the case, it's a benign (not life threatening) condition. If there's a lot of protein, treatment will be prescribed by your doctor. You can help by not eating too much salt. As long as you get treatment for it, there's no cause for you to worry.

Question: Cause of foamy urine other then proteinuria? i had a full 24hr urine test done and my results were 7 from a scale of 1-15, doctor said it was normal, my blood pressure is normal, as well. what are the causes of this other then proteinuria? it happens in public washrooms, and i drink 4+ litres of water a day. i body build so i do have enough carbs and protein could it be caused by exercise? yeh the rock, im 18 you fool

Answer: does the foam have a color? or does your urine have a distinctive odor other than the smell of regular urine? if not, the most probable cause of the foam is acidic urine. your pH level of you urine could be really acidic.