Sideroblastic Anemia

Question: tibc in sideroblastic anemia? Increased of decreased

Answer: Decreased, because of decreased transferrin levels.

Question: Does anyone know about Sideroblastic Anemia? Does anyone out there have Sideroblastic Anemia or know anyone that has it? My friend was diagnosed with it and it is really rare. We would love to know if there is anyone out there that has some experience with it who can tell us what we should be expecting in the coming years.

Answer: The sideroblastic anemias are a group of blood disorders in which the body has enough iron but is unable to use it to make hemoglobin, which carries oxygen in the blood. As a result, iron accumulates in the mitochondria of red blood cells, giving a ringed appearance to the nucleus (ringed sideroblast). There are three categories of sideroblastic anemias: inherited, acquired, and idiopathic (of unknown origin). The signs and symptoms can range from mild to severe, and include fatigue, breathing difficulties, and weakness. Enlargement of the liver or spleen may also occur. In severe cases, the increased levels of iron in the blood may lead to heart disease, liver damage, and kidney failure. Resources Leukemia & Lymphoma Society 1311 Mamaroneck Ave 3rd Floor White Plains, NY 10605 Tel: (914)949-5213 Fax: (914)949-6691 Tel: (800)955-4572 Email: infocenter@LLS.org Internet: http://www.LLS.org *** March of Dimes Birth Defects Foundation 1275 Mamaroneck Avenue White Plains, NY 10605 Tel: (914)428-7100 Fax: (914)997-4763 Tel: (888)663-4637 Email: Askus@marchofdimes.com Internet: http://www.marchofdimes.com ** NIH/National Heart, Lung and Blood Institute Information Center P.O. Box 30105 Bethesda, MD 20824-0105 Tel: (301)592-8573 Fax: (301)251-1223 Email: nhlbiinfo@rover.nhlbi.nih.gov ** Iron Disorders Institute P.O. Box 675 Taylors, SC 29687 USA Tel: 8642921175 Fax: 8642921878 Tel: 8885654766 Email: comments@irondisorders.org Internet: http://www.irondisorders.org For a Complete Report This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdbli… The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians. It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report. This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder. For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org