Factor VII

Question: Doctors, nurses, or anyone, Factor VII? Hi!! i am still working on my isp... and i need alittle more help... can anyone give me a site or anything to help me get the HISTORY of factor VII? like, when it was reconized, who reconized it, and what has been done since then. to all who will help... THANK YOU SOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO… MUCH... u have NO clue how much i need this... well may b u do... idk

Answer: There's not much on the history of Factor VII Discovered in 1951 - Alexander et al. Alexander, B., Goldstein, R., Landwehr, G. & Cook, C.D. (1951) Coagulation serum prothrombin conversion accelerator (SPCA) deficiency: a hitherto unrecognized coagulation defect with hemorrhage rectified by serum and serum fraction. Journal of Clinical Investigation, 30, 596–608.

Question: PROMTHROMBIN Time, Factor VII? my PT is 19.3 and PT INR 1.6 meaning a factor VII deficiency. So this basically means my blood clots slowly right? My doctor suggested wearing a medical alert bracelet just in case of an accident or if i was in labor etc. Judging by my PT time how important is it for me to get a medical alert bracelet and how severe is my situation, like am i really bad off or am i just above the norm? Thank you I was tested 3 times for this disorder. and each time it came back positive so i doubt that the labs were done incorrectly. I am having medical problems right now and that is why i was tested.

Answer: This result suggests that you are not severely affected so you shouldn't have any spontaneous bleeds. If you do have an operation or major trauma it is likely that you will need to be given a factor VII concentrate to help manage potential bleeding so I would definately get a bracelet stating your condition in order to help the doctors (and the laboratory) manage your condition properly.

Question: What were some of the contributing factors to Henry VII attaining the crown? apart from the help from the Stanleys in the Battle of Bosworth

Answer: Stanley helped him to attain the crown because he watched to see which direction the battle would go and when Richard decided to strike at Henry himself, he almost succeeded, slaughtering Henry's standard bearer and could have easily killed Henry, leading to Stanley's interferance. However, Henry VII didn't necessarily owe his success to the Stanley's, it was just one of many contributing factors. So, to make your answer longer you could include some of these other factors which could be argued to be as important if not more, such as the unpopularity of Richard III - I.e. People didn't like the fact he murdered his nephews and didn't approve of his usurpation, therefore making it easier for Henry to attain the crown.

Question: Do you have a clotting disorder? Statistical information requested? Not looking for people whose blood clots too quickly, but those who have trouble getting the bleeding to stop or in recurring reopening of wounds with subsequent bleeding. If so, please respond: TYPE: (haemophilia, von Willebrand's, factor VII, etc., if you know) Age: Sex: Ethnic Background:(northern European, Southern European etc - not necessary to be country-specific) Severity: 1-Occasional 2-Frequent but Mild 3-Frequent and Severe 4-Life Threatening Additional: Wounds reopen and bleed hours/days later Other: Please specify- e.g. 15 blood transfusions last year.

Answer: I dont thibnk yours is an appropriate method to find statiatics. Anyway this is a internet survey i just found; see if this hjelps you: Hospitalization statistics for Bleeding disorders: The following are statistics from various sources about hospitalizations and Bleeding disorders: 0.031% (3,924) of hospital consultant episodes were for coagulation defects in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 83% of hospital consultant episodes for coagulation defects required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 44% of hospital consultant episodes for coagulation defects were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 56% of hospital consultant episodes for coagulation defects were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 55% of hospital consultant episodes for coagulation defects required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 5.6 days was the mean length of stay in hospitals for coagulation defects in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 2 days was the median length of stay in hospitals for coagulation defects in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 51 was the mean age of patients hospitalised for coagulation defects in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 44% of hospital consultant episodes for coagulation defects occurred in 15-59 year olds in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 27% of hospital consultant episodes for coagulation defects occurred in people over 75 in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 31% of hospital consultant episodes for coagulation defects were single day episodes in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 0.022% (11,302) of hospital bed days were for coagulation defects in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 0.097% (12,320) of hospital consultant episodes were for purpura and other haemorrhagic conditions in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 94% of hospital consultant episodes for purpura and other haemorrhagic conditions required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 47% of hospital consultant episodes for purpura and other haemorrhagic conditions were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 53% of hospital consultant episodes for purpura and other haemorrhagic conditions were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 40% of hospital consultant episodes for purpura and other haemorrhagic conditions required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 3.6 days was the mean length of stay in hospitals for purpura and other haemorrhagic conditions in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 1 days was the median length of stay in hospitals for purpura and other haemorrhagic conditions in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 40 was the mean age of patients hospitalised for purpura and other haemorrhagic conditions in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 38% of hospital consultant episodes for purpura and other haemorrhagic conditions occurred in 15-59 year olds in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 14% of hospital consultant episodes for purpura and other haemorrhagic conditions occurred in people over 75 in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 48% of hospital consultant episodes for purpura and other haemorrhagic conditions were single day episodes in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 0.038% (19,844) of hospital bed days were for purpura and other haemorrhagic conditions in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 0.002% (305) of hospital consultant episodes were for haemorrhage in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 79% of hospital consultant episodes for haemorrhage required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 49% of hospital consultant episodes for haemorrhage were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 51% of hospital consultant episodes for haemorrhage were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 75% of hospital consultant episodes for haemorrhage required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 6.2 days was the mean length of stay in hospitals for haemorrhage in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 3 days was the median length of stay in hospitals for haemorrhage in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 58 was the mean age of patients hospitalised for haemorrhage in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 35% of hospital consultant episodes for haemorrhage occurred in 15-59 year olds in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 31% of hospital consultant episodes for haemorrhage occurred in people over 75 in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 11% of hospital consultant episodes for haemorrhage were single day episodes in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03) 0.002% (1,206) of hospital bed days were for haemorrhage in England 2002-03 (Hospital Episode Statistics, Department of Health, England,

Question: How was the Protestant Reformation a political movement.? I have a debate on Thursday agreeing with how the Protestant Reformation in Europe was mostly a political movement, rather than a religious one. Also : - Was it a product of great ideas, or the result of socio-economic forces of the time? - Was Henry VII motivated by political desire or other factors? I just need some ideas.

Answer: The Protestant Reformation in England was very much tied up with politics. It was for political reasons that Henry the Eighth felt the need to break with the Church of Rome, and it was largely because of politics that Queen Elizabeth was compelled to reaffirm the Protestant stance of England whether she really desired to or not. Protestantism ... was not unwelcome. It gave the monarch independence from Rome, and a greater control over ecclesiastical affairs in the kingdom. Protestantism was also advantageous to those at the top of the social pyramid. With the dissolution of the monasteries in the mid fifteen twenties, church land fell to the Crown, and Henry shrewdly sold much of it to the nobility and gentry, which not only increased their economic and political power, but also ensured that they had a vested interest in the survival of the new religion. http://www.lycos.com/info/protestant-ref…

Question: Does anyone know much about the Palm Treo? I am considering getting a Palm Treo as my new cell phone. My company's software supports intellisync with the Palm III, V and VII. Does anyone know if the Treo is technically one of these? This will be the deciding factor. I can't find anything that states this for sure or not on the website. The Treo uses Palm OS 5.4 and when I searched for Treo on the website the help file for the Palm 5 came up, but I still want to make sure before I spend the money. Yes, but is it structurally a Palm III, V, or VII?

Answer: The Palm III, V and VII are OLD OLD OLD Palm devices. I would be very surprised if there is much similarity between them and the Treo devices. Treo was originally developed by another company (Handspring) that was bought out by Palm, so the 'genetics' of the two series are different. Besides, Palm now offers Treo's in both Palm and Windows OS. (PALM version is more stable, has better screen resolution but I'm an old Palm guy!) You need to start lobbying your company for more current PDA support.

Question: tell true or false ? i.The discovery, refinement, modeling and specification are a process of ____________. ii.__________is the technical kernel of any software engineering. iii.___________is one of the requirements elicitation techniques that translate needs of customers into technical requirements of software. iv. __________is a life cycle model that combines the linear nature of the Waterfall model and the iterative nature of the Prototyping model. v.The quality of a product ____________ depends how good client requirements and specifications have been conceived. vi.The extent to which the program is secure and its ability to recover quickly from failure is referred to __________________ that is one of the quality assurance product operation factor. vii.The risk analysis includes two primary activities namely ________________. viii.The ____________________, a product transition factor can be defined as effort needed to transfer a program to another system. ix.The goals & objectives sh

Answer: Ha Ha what are you? Moron? Is that true or false? Or fill up the gaps? Anyway, never mind. Do your own homework. It's better for you.

Question: Irregular period?? I'm 16 and I've been getting my period since 7th grade (I'm in 10th grade now.) My period is super irregular though...I only get it one or two times a year. I'm not taking any form of birth control and I'm not sexually active...So I'm not quite sure what's wrong. I do have a factor VII deficiency (it's mild, not severe), but I'm wondering if this has anything to do with it. My friends all think I'm lucky, but I'm starting to wonder if this is something seriously wrong with me...Is this normal?

Answer: Sorry to give you the old "go see your doc" answer, but there are so many things it could be. You could have a thyroid or parathyroid problem (what was causing mine, even though they thought I was too young for these problems), Polycystic Ovary Sydrome, changing your eating habits often/ not eating enough, or many other things. Being you're so young I don't think it's anything that's not treatable. Reproductive cancers at your age are beyond rare. I don't believe it's normal to only have 2 periods a year, but I don't think the cause is anything life threatening or that can't be taken care of. Good luck!

Question: For Doctors or Hematologists!? please help... I am doing a I.S.P. (independent study project) on a blood disorder called Factor VII Deficiency. On the internet i have been able to find sites but on the project u must have at least five different sources. if u could please give me a list of books or articles that explain how this disorder works. If u list a book please tell author and other information... if u list a article please write where the article came from and who wrote it. THANK YOU SOOOOOOO MUCH!!!!!!

Answer: Here are three standard Hematology textbooks which discuss Factor VII deficiency (proconvertin deficiency, Alxander's disease) Each of these three is a major textbook with a link to the chapter of relevance. You can get other data such a spublisher, etc, from the name of the text and the author of the article, both given. Wintrobe's Clinical Hematology By Maxwell Myer Wintrobe, John P. Greer 2800 pages http://books.google.com/books?id=VxRYvJb… Williams Hematology By Marshall A. Lichtman 1856 pages http://books.google.com/books?id=Ks8UGOz… Disorders of Thrombosis and Hemostasis: Clinical and Laboratory Practice By Rodger L. Bick 464 pages http://books.google.com/books?id=VxRYvJb… I realize that this is not the five resources you said you needed. Find a review article in a major professional journal on this subject in New England Journal of Medicine or Journal of the American Medical Association or Lancet or Mayo Clinic Proceedings or Annals of Internal Medicine or British Medical Journal. Major texts and review articles in major professional journals will make great print references. I can't get the print journal's content on the Internet, but you can in a medical library

Question: I have Hemophilia A and need help on a problem I have with it? I have hemophilia A and I have had bleeding in my hip joint. Because it was very painful I had to sleep curled up which lessened the pain to some extent. I had taken Factor VII every 12 hours until I had the bleeding stopped however since I had slept curled up a nerve was blocked and it soon stopped providing blood to my thigh muscle I soon had numbness there and then the doctor said my muscle was shrinking because I could not move the muscle at all and that I had to take electronic muscle simulation however this created a bleeding in my knee joint does anyone know how to exercise the muscle without using the electronic muscle simulation also is there another medicine other than Factor VII I have a clotting factor of 2.5% Oh and it was factor VIII, sorry also the doctors don't specify with thigh muscle it is though I cannot pull up my knee but I can pull back my knee however I don't know which thigh muscle it is. and the doctors say this is the biggest muscle in our whole body I am in Thailand not in USA so I don't believe there are factor 8 donating companies here.

Answer: Would help if I had more info. What is your clotting % without a bleed? I assume you are taking some type of recombinant factor like Xyntha (Wyeth) or Benefix. The only other type of treatment that I have ever got was the heat treated human plasma. You could try asking for that but doubt you would get it. To much danger of disease. When you say "Thigh muscle" do you mean inner or outer? I did a quick search on goggle and came up with a ton of sites. Before doing any of this I would make sure your bleed is under control. Another option would be to get the factor before the electronic muscle simulation. Anytime I get factor it brings my clotting levels up to normal for about 24 hours. By the way are you a factor 7 or 8? You said 7 but just wanted to make sure. Could of been a typo as factor 7's are rather rare. If the factor is costing to much may I suggest getting on contact with the Wyeth Factor Resource Program. The will donate up to 100,000 units ( I think) per year. Last I knew their phone number was 1-888-999-2349 Sorry for rambling. Contact me by email if you need some more info.