Klinefelter Syndrome

Question: what kinds of research is being done on klinefelter syndrome? i would just like to know what kinds of research is being done on klinefelter syndrome. thanks for the help.

Answer: I'm not sure what it is you want to know. Klinefelter's syndrome is well understood; it's not like they don't know what causes it. It's a basic genetic mutation in which a male has an extra X chromosome. There isn't any current potential for altering the genotype, if that is what you mean--? There are lots of studies about treatments for various problems typical for Kleinfelter's patients, including hormone replacement therapy, and there are studies about the population--psychology, neurological implications, prevalence of diseases. Many of these studies are very easy to find with a simple internet search--it's hard to direct you without a little more information about what you're looking for. Maybe you could clarify what you're curious about?

Question: What they Screen to find the Klinefelter Syndrome? Okay im doing a science project on the Klinefelter syndrome. in french. :P And i cant find the "techniques de depistage genetique" for the klinefelter syndrome. I have no idea what they would do.. apparently techniqies de depistage genetique is screening.. so please help?, its due tomorrow. and please help?

Answer: Klinefelter's is a chromosome abnormality: XXY instead of the normal XY for males. It will be picked up on a karyotype test (they look at the chromosomes in a cell during meiosis)

Question: How can I find out if I have Klinefelter's syndrome? Using wikipedia as my reference, I have diagnosed myself as having all the symptoms of klinefelter's syndrome (except for a confirmation of sterility/fertility). How do I get tested for a chromosomal disorder, and is it possible to have it done at a free clinic or at an unemployed-person discount? I am in Portland, OR...they are usually better here than most places for medical care to poor or homeless people- if you know about Oregon, as in where to go and what to ask, It would be a great help. Thanks in advance for your thoughtful and kind answers.

Answer: make a doctors appt. dont try to figure out what is wrong with you online many things have alot af the same symptoms.

Question: Can you think of a creative title for a Klinefelter's Syndrome paper? I need a creative title for my paper, but it cant have Klinefelter's Syndrome in the title.

Answer: "XXY and Why?" Kleinfelters genetic make up is XXY (an extra x chromosome) you could do the paper on how kleinfelters happens and what it means for someone who has it..........

Question: What is the number of chromosomes in Klinefelter syndrome and what is special for the karyotype? Also how does the chromosome abnormality arise?

Answer: 47. An extra X and a single Y. Non-disjunction again but this time you get the side with the extra chromosome instead of the one missing.

Question: Do you have to have any form of Retardation and be diagnosed with klinefelter's syndrome? I have a really low testosterone level and some of the other characteristics of klinefelter's syndrome. My doctor won't diagnose it sense i do not present with an retardation.

Answer: I would seek a second opinion about this. Retardation is not a hallmark of the condition as you can see. http://www.aaa.dk/TURNER/ENGELSK/KLINEN.HTM Klinefelter's syndrome is found in approximately 1 of 700 men, i.e. there are approximately 3600 boys and men with Klinefelter's syndrome in Denmark with 5 million inhabitants. Men usually have but one X and one Y chromosome, i.e. the chromosomeconstitution 46,XY. Men with Klinefelter's syndrome have more than one X chromosome, usually two X chromosomes, i.e. the chromosome constitution 47,XXY. At birth the testicles of Klinefelter boys are of normal size. When the testicles grow quickly in boys with normal chromosomes at the age of 11-12 years, the testicles of Klinefelter boys stay very small, as a rule only 2 cms. from pole to pole. Usually only few sperms are developed in the testicles, and men with Klinefelter's syndrome are as a rule infertile. Boys with Klinefelter's syndrome should be treated with testosterone, usually from the 11 or 12 years of age, best with Restandol tablets (Testosteroneundecanoat), which does not affect the liver, or with injections of other testosterone preparations. Klinefelter boys more often than other boys have delayed motor function, speech, and maturation development, which does not make them patients demanding special treatment. It is important that these boys at an early age go to a good day-care institution, and that there is a close cooperation between parents and day-care institution staff. If the speech development is delayed, it is important to get help from a speech-therapist for a period. Regarding the motor function development, the participation of parent/child in sports activities and group activities of any kind is of great value. The same is the case with regard to stimulating the delayed development in maturation. In this connection it must be mentioned, that it is also important to stimulate these boys to independence, and not in any way to overprotect them. Regarding the missing muscle development in puberty and late puberty, with increased tiredness and need for sleep, this can to a great extent be counteracted, and usually quite eliminated, by relevant testosterone treatment from the age of 11- 12 years. For better muscle development and motor function it is of great importance to take part in different sports activities through childhood. If Klinefelter boys grow up in a good, stable, and stimulating environment, the intelligence will be inside the normal area, though a little displaced, so that there are fewer than expected with an IQ over 110, but no increased frequency of boys with an IQ below 90. In a group of adult danish men with Klinefelter's syndrome an average IQ of 108 was found in comparison with 115 in a control group. However, all persons with Klinefelter's Syndrome, or their parents, can order the printed version free of charge.

Question: I have Klinefelter's syndrome, can I work as a nurse? I have Klinefelter's syndrome, can I work as a nurse? I am currently a 3rd-year nursing student. I'm suffering from learning difficulty due to lack of testosterone but somehow I managed to reach this far as a student nurse....

Answer: Why don't you get testosterone shots then?Must be hard on you this way. But my guess is that you qualify as a nurse.See no reasons why not Radius

Question: What is the sex chromosome composition of a person with Klinefelter syndrome? A.XXY. B.none of these C.XYY. D.XXX. E.XO.

Answer: It is XXY. The person receives an extra X because of non disjunction.

Question: What kind of mutations can Klinefelter's Syndrome cause in cats? I have a male calico cat with 6 toes on his front paws and eyes that look in opposite directions. I know that Klinefelter's (XXY chromosomes) can cause the calico pattern in a male, but would it also explain the extra toes and abnormal eyes? Also, could it cause mental retardation as well?

Answer: It does in humans if that's any help.

Question: Is it possible that I have Klinefelter's syndrome? I've been doing some research online and I think there may be a possibility that I have Klinefelter's (47,XXY). My sister however, has been diagnosed with Turner's syndrome (45,X). Is it possible for a brother and sister to both have these disorders?

Answer: yes it is possible. although the conditions are not linked, as in if you have 1 condition in the family it's not more likely you'll have another with the same or similar, well as far a turner syndrome anyway. Having a daughter with turners put you no more at risk of having another or another with a chromasome problem, as Turners is sporadic, it just happens, no reason, no cause, nothing either parent done or did not do. I know a lot about turner syndrome but very little about kleinfelters. what makes you think you may have kleinfelters??

Question: klinefelter syndrome? I'm not sure if I have klinefelter syndrome or if I do.... I am 14 and have gynecomastia and a high pitched voice. I am overweight but am very tall. I was reading up on klinefelter syndrome and i match all of the symptoms except for I'm not sterile, at least I dont think I am. I am going to make an appointment with an endocrinologist. So my question is if you can not be sterile and still have klinefelter syndrome

Answer: There is really no reason to go into this question until you have been examined and diagnosed. Most guys with klinefelters are sterile but some aren't. It's a small percentage. Get the exam an go from there. If you are diagnosed, the doctor will run several more tests.

Question: How did Klinefelter's syndrome affect your life? My son had Klinefelter's. He passed away several months ago from a heart defect. I'm curious to know how having Klinefelter's impacted your life.

Answer: I'm very sorry for your loss. I can only imagine what it would be like to lose a son. From what I understand, Klinefelter syndrome mostly affects fertility and hormones. He may have needed hormone therapy and would need to use assited reproductive technology and/or adoption in order to have children. Again, I'm very sorry for what happened to your son. Take care.

Question: Can hubby and I still have kids if he was diagnosed with Klinefelter syndrome? What r the treatments/results? Is there a chance with that Syndrome he can still have kids? Or our chances shot out? I have read up on it, but I want to here real life stories.

Answer: Klinefelter syndrome is associated with infertility but one of its type called Mosaicism which is observed in 10 % can be fertile.Hence it depends on what is the type of klinefelter syndrome your hubby has.If he got klinefelter syndrome mosaicism then you might have more chances of having a kid.Do not loose hope though as there are reports of births from a nonmosaic as well.The reported cases however uses the process of Intracytoplasmic sperm injection, in which a spermatozoon is injected into an ovum in vitro.The reported cases can de found on this site: http://content.nejm.org/cgi/content/extr…

Question: Klinefelter Syndrome / are there any support groups out there? Klinefelter syndorme is a cromasonal abnormality. These males have an extra "X" cromasone. I need to meet / talk to other parents of adult persons with this syndrome.

Answer: Try this site I found

Question: the reason why my doctor is injecting me with testosterone is cause i have klinefelter syndrome ? i hate having this syndrome and the dosage is 200mg and i only get a shot every two weeks what i don't get is it feels like i took viagar that last's up to two weeks straight or even a year

Answer: Being on testosterone replacement therapy can make your libido go high & cause frequent erections, but in my experience, it's better than the alternative. Personally, I think you might do better on 100 mg of testosterone per week, as there is less conversion to estrogen & less of an emotional roller coaster experience. But if this works for you without causing emotional issues or gynecomastia, stick with it.

Question: I'm just curious to know how many people out there know what klinefelter syndrome is? because my brother has it, and i feel like many people don't know what it is.

Answer: I am familiar with it, but I am a nurse. A lot of people don't know what it is, it is not common and not something you hear about often.